Percolation as a mechanism to explain atrial fractionated electrograms and reentry in a fibrosis model based on imaging data
Idioma
en
Article de revue
Este ítem está publicado en
Heart Rhythm. 2016-07, vol. 13, n° 7, p. 1536-1543
Elsevier
Resumen en inglés
Complex fractionated atrial electrograms (CFAEs) have long been associated with proarrhythmic alterations in atrial structure or electrophysiology. Structural alterations disrupt and slow smoothly propagating wavefronts, ...Leer más >
Complex fractionated atrial electrograms (CFAEs) have long been associated with proarrhythmic alterations in atrial structure or electrophysiology. Structural alterations disrupt and slow smoothly propagating wavefronts, leading to wavebreaks and electrogram (EGM) fractionation, but the exact nature and characteristics for arrhythmia remain unknown. Clinically, in atrial fibrillation (AF) patients, increases in frequency, whether by pacing or fibrillation, increase EGM fractionation and duration, and reentry can occur in relation with the conduction disturbance. Recently, percolation has been proposed as an arrhythmogenic mechanism, but its role in AF has not been investigated.< Leer menos
Palabras clave en inglés
Atrial fibrillation
Atrial fibrosis
Cardiac electrophysiology
Computer modeling
DE-MRI
Fractionated electrogram
Percolation
Orígen
Importado de HalCentros de investigación