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hal.structure.identifierModélisation Mathématique pour l'Oncologie [MONC]
hal.structure.identifierInstitut de Mathématiques de Bordeaux [IMB]
dc.contributor.authorCIAVOLELLA, Giorgia
hal.structure.identifierUniversité de Lyon
hal.structure.identifierInstitut Camille Jordan [ICJ]
hal.structure.identifierModélisation mathématique, calcul scientifique [MMCS]
dc.contributor.authorDAVID, Noemi
hal.structure.identifierUniversité de Lille
hal.structure.identifierLaboratoire Paul Painlevé - UMR 8524 [LPP]
hal.structure.identifierSorbonne Université [SU]
hal.structure.identifierLaboratoire Jacques-Louis Lions [LJLL (UMR_7598)]
hal.structure.identifierModelling and Analysis for Medical and Biological Applications [MAMBA]
dc.contributor.authorPOULAIN, Alexandre
dc.date.issued2024-02-06
dc.identifier.issn1463-9963
dc.description.abstractEnMotivated by biological applications on tumour invasion through thin membranes, we study a porous-medium type equation where the density of the cell population evolves under Darcy's law, assuming continuity of both the density and flux velocity on the thin membrane which separates two domains. The drastically different scales and mobility rates between the membrane and the adjacent tissues lead to consider the limit as the thickness of the membrane approaches zero. We are interested in recovering the <i>effective interface problem</i>and the transmission conditions on the limiting zero-thickness surface, formally derived by Chaplain et al., (2019), which are compatible with nonlinear generalized Kedem-Katchalsky ones. Our analysis relies on <i>a priori<i> estimates and compactness arguments as well as on the construction of a suitable extension operator which allows to deal with the degeneracy of the mobility rate in the membrane, as its thickness tends to zero.
dc.language.isoen
dc.publisherEuropean Mathematical Society
dc.subject.enMembrane boundary conditions
dc.subject.enEffective interface
dc.subject.enPorous medium equation
dc.subject.enNonlinear reaction-diffusion equations
dc.subject.enTumour growth models
dc.title.enEffective interface conditions for a porous medium type problem
dc.typeArticle de revue
dc.identifier.doi10.4171/ifb/505
dc.subject.halMathématiques [math]/Equations aux dérivées partielles [math.AP]
dc.description.sponsorshipEuropeAsymptotic approach to spatial and dynamical organizations
dc.description.sponsorshipEuropeInternational Doctoral Training in Mathematical Sciences in Paris
bordeaux.journalInterfaces and Free Boundaries : Mathematical Analysis, Computation and Applications
bordeaux.peerReviewedoui
hal.identifierhal-03231456
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-03231456v1
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