Modelling the dynamics of host-parasite interactions: basic principles
EZANNO, Pauline
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
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École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
EZANNO, Pauline
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
< Réduire
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Langue
en
Chapitre d'ouvrage
Ce document a été publié dans
New Frontiers of Molecular Epidemiology of Infectious Diseases, New Frontiers of Molecular Epidemiology of Infectious Diseases. 2012p. 79-101
Springer Science+Business Media B.V.
Résumé en anglais
Mathematical modelling is a valuable tool for the analysis of the infectious diseases spread. Dynamical models may help to represent and summarise available knowledge on transmission and disease evolution, to test assumptions ...Lire la suite >
Mathematical modelling is a valuable tool for the analysis of the infectious diseases spread. Dynamical models may help to represent and summarise available knowledge on transmission and disease evolution, to test assumptions and analyse scenarios, and to predict outcomes of the host-pathogen interactions. This chapter aims at introducing basic concepts and methods of epidemiological modelling, in order to provide a starting point for further developments. After positioning modelling in the process of disease investigation, we first present the main principles of model building and analysis, using simple biological and also mathematical systems. We then provide an overview of the methods that can be employed to describe more complex systems. Last, we illustrate how the modelling approach may help for different practical purposes, including evaluation of control strategies. A brief conclusion discusses the challenge of including genetic and molecular variability in epidemiological modelling.< Réduire
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