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Arm and ankle blood pressure indices, and peripheral artery disease, and mortality: a cohort study.

dc.rights.licenseopenen_US
hal.structure.identifierBiologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases
dc.contributor.authorMOHAMMEDI, Kamel
dc.contributor.authorPIGEYRE, Marie
dc.contributor.authorBOSCH, Jackie
dc.contributor.authorYUSUF, Salim
dc.contributor.authorGERSTEIN, Hertzel C
dc.date.accessioned2024-03-25T14:52:20Z
dc.date.available2024-03-25T14:52:20Z
dc.date.issued2024-03-01
dc.identifier.issn1522-9645en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/188962
dc.description.abstractEnFew studies have compared arm and ankle blood pressures (BPs) with regard to peripheral artery disease (PAD) and mortality. These relationships were assessed using data from three large prospective clinical trials. Baseline BP indices included arm systolic BP (SBP), diastolic BP (DBP), pulse pressure (arm SBP minus DBP), ankle SBP, ankle-brachial index (ABI, ankle SBP divided by arm SBP), and ankle-pulse pressure difference (APPD, ankle SBP minus arm pulse pressure). These measurements were categorized into four groups using quartiles. The outcomes were PAD (the first occurrence of either peripheral revascularization or lower-limb amputation for vascular disease), the composite of PAD or death, and all-cause death. Among 40 747 participants without baseline PAD (age 65.6 years, men 68.3%, diabetes 50.2%) from 53 countries, 1071 (2.6%) developed PAD, and 4955 (12.2%) died during 5 years of follow-up. Incident PAD progressively rose with higher arm BP indices and fell with ankle BP indices. The strongest relationships were noted for ankle BP indices. Compared with people whose ankle BP indices were in the highest fourth, adjusted hazard ratios (95% confidence interval) for each lower fourth were 1.64 (1.31-2.04), 2.59 (2.10-3.20), and 4.23 (3.44-5.21) for ankle SBP; 1.19 (0.95-1.50), 1.66 (1.34-2.05), and 3.34 (2.75-4.06) for ABI; and 1.41 (1.11-1.78), 2.04 (1.64-2.54), and 3.63 (2.96-4.45) for APPD. Similar patterns were observed for mortality. Ankle BP indices provided the highest c-statistics and classification indices in predicting future PAD beyond established risk factors. Ankle BP indices including the ankle SBP and the APPD best predicted PAD and mortality.
dc.language.isoENen_US
dc.subject.enAnkle; Arm; Blood pressure; Mortality; Peripheral artery disease
dc.title.enArm and ankle blood pressure indices, and peripheral artery disease, and mortality: a cohort study.
dc.title.alternativeEur Heart Jen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1093/eurheartj/ehae087en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologie
dc.identifier.pubmed38426892en_US
bordeaux.journalEuropean Heart Journalen_US
bordeaux.hal.laboratoriesBiologie des maladies cardiovasculaires (BMC) - UMR 1034en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-04737778
hal.version1
hal.date.transferred2024-10-15T12:25:02Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=European%20Heart%20Journal&rft.date=2024-03-01&rft.eissn=1522-9645&rft.issn=1522-9645&rft.au=MOHAMMEDI,%20Kamel&PIGEYRE,%20Marie&BOSCH,%20Jackie&YUSUF,%20Salim&GERSTEIN,%20Hertzel%20C&rft.genre=article


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