Mostrar el registro sencillo del ítem

dc.rights.licenseopenen_US
dc.contributor.authorGODIN, O
dc.contributor.authorOLIÉ, E
dc.contributor.authorFOND, G
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorAOUIZERATE, Bruno
IDREF: 069471851
dc.contributor.authorAUBIN, V
dc.contributor.authorBELLIVIER, F
dc.contributor.authorBELZEAUX, R
dc.contributor.authorCOURTET, P
dc.contributor.authorDUBERTRET, C
dc.contributor.authorHAFFEN, E
dc.contributor.authorLEFRERE, A
dc.contributor.authorLLORCA, P M
dc.contributor.authorPOLOSAN, M
dc.contributor.authorROUX, P
dc.contributor.authorSAMALIN, L
dc.contributor.authorSCHWAN, R
dc.contributor.authorLEBOYER, M
dc.contributor.authorETAIN, B
dc.date.accessioned2024-03-20T09:21:19Z
dc.date.available2024-03-20T09:21:19Z
dc.date.issued2024-03-01
dc.identifier.issn1600-0447en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/188870
dc.description.abstractEnMetabolic syndrome (MetS) is a cluster of components including abdominal obesity, hyperglycemia, hypertension, and dyslipidemia. MetS is highly prevalent in individuals with bipolar disorders (BD) with an estimated global rate of 32.6%. Longitudinal data on incident MetS in BD are scarce and based on small sample size. The objectives of this study were to estimate the incidence of MetS in a large longitudinal cohort of 1521 individuals with BD and to identify clinical and biological predictors of incident MetS. Participants were recruited from the FondaMental Advanced Center of Expertise for Bipolar Disorder (FACE-BD) cohort and followed-up for 3 years. MetS was defined according to the International Diabetes Federation criteria. Individuals without MetS at baseline but with MetS during follow-up were considered as having incident MetS. A logistic regression model was performed to estimate the adjusted odds ratio and its corresponding 95% confidence interval (CI) for an association between each factor and incident MetS during follow-up. We applied inverse probability-of-censoring weighting method to minimize selection bias due to loss during follow-up. Among individuals without MetS at baseline (n = 1521), 19.3% developed MetS during follow-up. Multivariable analyses showed that incident MetS during follow-up was significantly associated with male sex (OR = 2.2, 95% CI = 1.7-3.0, p < 0.0001), older age (OR = 2.14, 95% CI = 1.40-3.25, p = 0.0004), presence of a mood recurrence during follow-up (OR = 1.91, 95% CI = 1.22-3.00, p = 0.0049), prolonged exposure to second-generation antipsychotics (OR = 1.56, 95% CI = 0.99, 2.45, p = 0.0534), smoking status at baseline (OR = 1.30, 95% CI = 1.00-1.68), lifetime alcohol use disorders (OR = 1.33, 95% CI = 0.98-1.79), and baseline sleep disturbances (OR = 1.04, 95% CI = 1.00-1.08), independently of the associations observed for baseline MetS components. We observed a high incidence of MetS during a 3 years follow-up (19.3%) in individuals with BD. Identification of predictive factors should help the development of early interventions to prevent or treat early MetS.
dc.description.sponsorshipFondaMental-Cohortes - ANR-10-COHO-0010en_US
dc.description.sponsorshipSorbonne Universités à Paris pour l'Enseignement et la Rechercheen_US
dc.language.isoENen_US
dc.subject.enHumans
dc.subject.enMale
dc.subject.enMetabolic Syndrome
dc.subject.enLongitudinal Studies
dc.subject.enBipolar Disorder
dc.subject.enRisk Factors
dc.subject.enIncidence
dc.subject.enAlcoholism
dc.title.enIncidence and predictors of metabolic syndrome onset in individuals with bipolar disorders: A longitudinal study from the FACE-BD cohort.
dc.title.alternativeActa Psychiatr Scanden_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1111/acps.13655en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed38268142en_US
bordeaux.journalActa Psychiatrica Scandinavicaen_US
bordeaux.page207-218en_US
bordeaux.volume149en_US
bordeaux.hal.laboratoriesNutriNeuro (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286en_US
bordeaux.issue3en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionINRAEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.jtitle=Acta%20Psychiatrica%20Scandinavica&amp;rft.date=2024-03-01&amp;rft.volume=149&amp;rft.issue=3&amp;rft.spage=207-218&amp;rft.epage=207-218&amp;rft.eissn=1600-0447&amp;rft.issn=1600-0447&amp;rft.au=GODIN,%20O&amp;OLI%C3%89,%20E&amp;FOND,%20G&amp;AOUIZERATE,%20Bruno&amp;AUBIN,%20V&amp;rft.genre=article


Archivos en el ítem

ArchivosTamañoFormatoVer

No hay archivos asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem