Maternal occupational exposure to carbonaceous nanoscale particles and neurodevelopmental outcomes in early childhood: Analysis of the French Longitudinal Study of Children - Elfe study
dc.rights.license | open | en_US |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | MANANGAMA, Guyguy | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | GALERA, Cedric
ORCID: 0000-0003-0549-9608 IDREF: 110034007 | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | AUDIGNON, Sabyne | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | GRAMOND, Celine | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | TARTAGLIA, Marie | |
dc.contributor.author | ZAROS, Cecile | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | TEYSSEIRE, Raphaelle | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | BROCHARD, Patrick | |
dc.contributor.author | SENTILHES, Loic | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | DELVA, Fleur | |
dc.date.accessioned | 2024-03-14T15:14:00Z | |
dc.date.available | 2024-03-14T15:14:00Z | |
dc.date.issued | 2024-02-02 | |
dc.identifier.issn | 1096-0953 (Electronic) 0013-9351 (Linking) | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/188802 | |
dc.description.abstractEn | OBJECTIVE: To investigate the association between occupational exposures to carbonaceous unintentionally emitted nanoscale particles (UNPs) during pregnancy and the child's language development and behaviour at two years old. METHODS: Using data from the French Longitudinal Study of Childhood - ELFE, we selected mothers who worked during pregnancy and their children. Exposure to carbonaceous UNPs was assessed by the MatPUF (job-exposure matrix for ultrafine particles). Children's lexical development was analysed using 'the Mac Arthur - Bates communicative development inventories-words and sentences-short form' (MB-CDI) in a multivariate binary logistic regression. Their risk for autism spectrum disorders was studied using 'the Modified-CHecklist for Autism in Toddler' (M-CHAT) according to the recommended thresholds (low risk = 0-2; intermediate risk = 3-6 and high risk = 7-23) in unordered multinomial logistic regression models. RESULTS: Maternal occupational exposure to carbonaceous UNPs was associated with delayed child language development (ORadj: 1.34; 95 % CI: 1.00, 1.80) but not with behavioural disorders (autism spectrum disorders) at two years old. CONCLUSION: This is the first epidemiological study to show a significant association between maternal occupational exposure to carbonaceous nanoscale particles and child language development at 2 years old. | |
dc.language.iso | EN | en_US |
dc.subject.en | Carbonaceous nanoscale particles | |
dc.subject.en | ELFE cohort | |
dc.subject.en | Neurodevelopmental disorders | |
dc.subject.en | Occupational exposure | |
dc.title.en | Maternal occupational exposure to carbonaceous nanoscale particles and neurodevelopmental outcomes in early childhood: Analysis of the French Longitudinal Study of Children - Elfe study | |
dc.title.alternative | Environ Res | en_US |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1016/j.envres.2024.118364 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
dc.identifier.pubmed | 38309566 | en_US |
bordeaux.journal | Environmental Research | en_US |
bordeaux.page | 118364 | en_US |
bordeaux.volume | 248 | en_US |
bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | INSERM | en_US |
bordeaux.team | EPICENE_BPH | en_US |
bordeaux.team | HEALTHY_BPH | en_US |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
hal.identifier | hal-04505170 | |
hal.version | 1 | |
hal.date.transferred | 2024-03-14T15:14:02Z | |
hal.popular | non | en_US |
hal.audience | Internationale | en_US |
hal.export | true | |
dc.rights.cc | Pas de Licence CC | en_US |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Environmental%20Research&rft.date=2024-02-02&rft.volume=248&rft.spage=118364&rft.epage=118364&rft.eissn=1096-0953%20(Electronic)%200013-9351%20(Linking)&rft.issn=1096-0953%20(Electronic)%200013-9351%20(Linking)&rft.au=MANANGAMA,%20Guyguy&GALERA,%20Cedric&AUDIGNON,%20Sabyne&GRAMOND,%20Celine&TARTAGLIA,%20Marie&rft.genre=article |
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