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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorMANANGAMA, Guyguy
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorGALERA, Cedric
ORCID: 0000-0003-0549-9608
IDREF: 110034007
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorAUDIGNON, Sabyne
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorGRAMOND, Celine
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorTARTAGLIA, Marie
dc.contributor.authorZAROS, Cecile
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorTEYSSEIRE, Raphaelle
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBROCHARD, Patrick
dc.contributor.authorSENTILHES, Loic
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDELVA, Fleur
dc.date.accessioned2024-03-14T15:14:00Z
dc.date.available2024-03-14T15:14:00Z
dc.date.issued2024-02-02
dc.identifier.issn1096-0953 (Electronic) 0013-9351 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/188802
dc.description.abstractEnOBJECTIVE: To investigate the association between occupational exposures to carbonaceous unintentionally emitted nanoscale particles (UNPs) during pregnancy and the child's language development and behaviour at two years old. METHODS: Using data from the French Longitudinal Study of Childhood - ELFE, we selected mothers who worked during pregnancy and their children. Exposure to carbonaceous UNPs was assessed by the MatPUF (job-exposure matrix for ultrafine particles). Children's lexical development was analysed using 'the Mac Arthur - Bates communicative development inventories-words and sentences-short form' (MB-CDI) in a multivariate binary logistic regression. Their risk for autism spectrum disorders was studied using 'the Modified-CHecklist for Autism in Toddler' (M-CHAT) according to the recommended thresholds (low risk = 0-2; intermediate risk = 3-6 and high risk = 7-23) in unordered multinomial logistic regression models. RESULTS: Maternal occupational exposure to carbonaceous UNPs was associated with delayed child language development (ORadj: 1.34; 95 % CI: 1.00, 1.80) but not with behavioural disorders (autism spectrum disorders) at two years old. CONCLUSION: This is the first epidemiological study to show a significant association between maternal occupational exposure to carbonaceous nanoscale particles and child language development at 2 years old.
dc.language.isoENen_US
dc.subject.enCarbonaceous nanoscale particles
dc.subject.enELFE cohort
dc.subject.enNeurodevelopmental disorders
dc.subject.enOccupational exposure
dc.title.enMaternal occupational exposure to carbonaceous nanoscale particles and neurodevelopmental outcomes in early childhood: Analysis of the French Longitudinal Study of Children - Elfe study
dc.title.alternativeEnviron Resen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.envres.2024.118364en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed38309566en_US
bordeaux.journalEnvironmental Researchen_US
bordeaux.page118364en_US
bordeaux.volume248en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamEPICENE_BPHen_US
bordeaux.teamHEALTHY_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04505170
hal.version1
hal.date.transferred2024-03-14T15:14:02Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Environmental%20Research&rft.date=2024-02-02&rft.volume=248&rft.spage=118364&rft.epage=118364&rft.eissn=1096-0953%20(Electronic)%200013-9351%20(Linking)&rft.issn=1096-0953%20(Electronic)%200013-9351%20(Linking)&rft.au=MANANGAMA,%20Guyguy&GALERA,%20Cedric&AUDIGNON,%20Sabyne&GRAMOND,%20Celine&TARTAGLIA,%20Marie&rft.genre=article


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