Mapping Cognitive Trajectories and Detecting Early Dementia Using the Mini-Mental State Examination Cognitive Charts: Application to the French Three-City Cohort
| dc.rights.license | open | en_US |
| dc.contributor.author | NORTON, Joanna | |
| dc.contributor.author | GUTIERREZ, Laure-Anne | |
| dc.contributor.author | GOURDEAU, Christian | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | AMIEVA, Helene | |
| dc.contributor.author | BERNIER, Patrick | |
| dc.contributor.author | BERR, Claudine | |
| dc.date.accessioned | 2024-03-13T08:22:52Z | |
| dc.date.available | 2024-03-13T08:22:52Z | |
| dc.date.issued | 2024-02-19 | |
| dc.identifier.issn | 1875-8908 (Electronic) 1387-2877 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/188749 | |
| dc.description.abstractEn | The Cognitive Quotient (QuoCo) classification algorithm monitoring decline on age- and education-adjusted Mini-Mental State Examination (MMSE)-derived cognitive charts has proved superior to the conventionally-used cut-off for identifying incident dementia; however, it remains to be tested in different settings. Data were drawn from the Three-City Cohort to 1) assess the screening accuracy of the QuoCo, and 2) compare its performance to that of serial MMSE tests applying different cut-offs. For the QuoCo, sensitivity was 74.2 (95% CI: 71.4-76.8) and specificity 84.1 (83.6-84.7) and for the MMSE < 24, 64.1 (61.1-67.0) and 94.8 (94.4-95.1), respectively; whereas overall accuracy and sensitivity was highest for MMSE cut-offs <25 and <26. User-friendly charts for mapping cognitive trajectories over visits with an alert for potentially 'abnormal' decline can be of practical use and encourage regular monitoring in primary care where the <24 cut-off is still widely used despite its poor sensitivity. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | cognitive decline | |
| dc.subject.en | dementia | |
| dc.subject.en | early detection | |
| dc.subject.en | education | |
| dc.subject.en | Age | |
| dc.subject.en | Alzheimer’s disease | |
| dc.title.en | Mapping Cognitive Trajectories and Detecting Early Dementia Using the Mini-Mental State Examination Cognitive Charts: Application to the French Three-City Cohort | |
| dc.title.alternative | J Alzheimers Dis | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.3233/JAD-231176 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 38393910 | en_US |
| bordeaux.journal | Journal of Alzheimer's disease | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | ACTIVE_BPH | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
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| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
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