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dc.rights.licenseopenen_US
dc.contributor.authorNORTON, Joanna
dc.contributor.authorGUTIERREZ, Laure-Anne
dc.contributor.authorGOURDEAU, Christian
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorAMIEVA, Helene
dc.contributor.authorBERNIER, Patrick
dc.contributor.authorBERR, Claudine
dc.date.accessioned2024-03-13T08:22:52Z
dc.date.available2024-03-13T08:22:52Z
dc.date.issued2024-02-19
dc.identifier.issn1875-8908 (Electronic) 1387-2877 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/188749
dc.description.abstractEnThe Cognitive Quotient (QuoCo) classification algorithm monitoring decline on age- and education-adjusted Mini-Mental State Examination (MMSE)-derived cognitive charts has proved superior to the conventionally-used cut-off for identifying incident dementia; however, it remains to be tested in different settings. Data were drawn from the Three-City Cohort to 1) assess the screening accuracy of the QuoCo, and 2) compare its performance to that of serial MMSE tests applying different cut-offs. For the QuoCo, sensitivity was 74.2 (95% CI: 71.4-76.8) and specificity 84.1 (83.6-84.7) and for the MMSE <  24, 64.1 (61.1-67.0) and 94.8 (94.4-95.1), respectively; whereas overall accuracy and sensitivity was highest for MMSE cut-offs <25 and <26. User-friendly charts for mapping cognitive trajectories over visits with an alert for potentially 'abnormal' decline can be of practical use and encourage regular monitoring in primary care where the <24 cut-off is still widely used despite its poor sensitivity.
dc.language.isoENen_US
dc.subject.encognitive decline
dc.subject.endementia
dc.subject.enearly detection
dc.subject.eneducation
dc.subject.enAge
dc.subject.enAlzheimer’s disease
dc.title.enMapping Cognitive Trajectories and Detecting Early Dementia Using the Mini-Mental State Examination Cognitive Charts: Application to the French Three-City Cohort
dc.title.alternativeJ Alzheimers Disen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.3233/JAD-231176en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed38393910en_US
bordeaux.journalJournal of Alzheimer's diseaseen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamACTIVE_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04591228
hal.version1
hal.date.transferred2024-05-28T14:39:40Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.jtitle=Journal%20of%20Alzheimer's%20disease&amp;rft.date=2024-02-19&amp;rft.eissn=1875-8908%20(Electronic)%201387-2877%20(Linking)&amp;rft.issn=1875-8908%20(Electronic)%201387-2877%20(Linking)&amp;rft.au=NORTON,%20Joanna&amp;GUTIERREZ,%20Laure-Anne&amp;GOURDEAU,%20Christian&amp;AMIEVA,%20Helene&amp;BERNIER,%20Patrick&amp;rft.genre=article


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