Influence of age, circadian and homeostatic processes on inhibitory motor control: a Go/Nogo task study.
| dc.rights.license | open | en_US |
| hal.structure.identifier | Sommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY] | |
| dc.contributor.author | SAGASPE, Patricia | |
| hal.structure.identifier | Sommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY] | |
| dc.contributor.author | TAILLARD, Jacques
ORCID: 0000-0001-9067-8189 IDREF: 229930786 | |
| hal.structure.identifier | Institut de Santé Publique, d'Epidémiologie et de Développement [ISPED] | |
| dc.contributor.author | AMIÉVA, Hélène | |
| hal.structure.identifier | Institut de Médecine et de Physiologie Spatiales [MEDES] | |
| dc.contributor.author | BECK, Arnaud | |
| hal.structure.identifier | Université Toulouse III - Paul Sabatier [UT3] | |
| dc.contributor.author | RASCOL, Olivier | |
| hal.structure.identifier | Institut de Santé Publique, d'Epidémiologie et de Développement [ISPED] | |
| dc.contributor.author | DARTIGUES, Jean-François | |
| hal.structure.identifier | Sommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY] | |
| dc.contributor.author | CAPELLI, Aurore | |
| hal.structure.identifier | Sommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY] | |
| dc.contributor.author | PHILIP, Pierre | |
| dc.date.accessioned | 2023-12-04T15:01:07Z | |
| dc.date.available | 2023-12-04T15:01:07Z | |
| dc.date.issued | 2012-06-25 | |
| dc.identifier.issn | 1932-6203 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/186344 | |
| dc.description.abstractEn | The contribution of circadian system and sleep pressure influences on executive performance as a function of age has never been studied. The aim of our study was to determine the age-related evolution of inhibitory motor control (i.e., ability to suppress a prepotent motor response) and sustained attention under controlled high or low sleep pressure conditions. 14 healthy young males (mean age = 23 ± 2.7; 20-29 years) and 11 healthy older males (mean age = 68 ± 1.4; 66-70 years) were recruited. The volunteers were placed for 40 hours in "constant routine". In the "Sleep Deprivation SD" condition, the volunteer was kept awake for 40 hours to obtain a high sleep pressure condition interacting with the circadian process. In the "NAP" condition, the volunteer adopted a short wake/sleep cycle (150/75 min) resulting in a low sleep pressure condition to counteract the homeostatic pressure and investigate the circadian process. Performances were evaluated by a simple reaction time task and a Go/Nogo task repeated every 3H45. In the SD condition, inhibitory motor control (i.e., ability to inhibit an inappropriate response) was impaired by extended wakefulness equally in both age groups (P<.01). Sustained attention (i.e. ability to respond accurately to appropriate stimuli) on the executive task decreased under sleep deprivation in both groups, and even more in young participants (P<.05). In the NAP condition, age did not influence the time course of inhibitory motor control or sustained attention. In the SD and NAP conditions, older participants had a less fluctuating reaction time performance across time of day than young participants (P<.001). Aging could be a protective factor against the effects of extended wakefulness especially on sustained attention failures due to an attenuation of sleep pressure with duration of time awake. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.subject.en | Adult | |
| dc.subject.en | Age Factors | |
| dc.subject.en | Aged | |
| dc.subject.en | Aging | |
| dc.subject.en | Attention | |
| dc.subject.en | Circadian Rhythm | |
| dc.subject.en | Homeostasis | |
| dc.subject.en | Humans | |
| dc.subject.en | Male | |
| dc.subject.en | Neuropsychological Tests | |
| dc.subject.en | Psychomotor Performance | |
| dc.subject.en | Reaction Time | |
| dc.subject.en | Sleep | |
| dc.subject.en | Sleep Deprivation | |
| dc.subject.en | Wakefulness | |
| dc.title.en | Influence of age, circadian and homeostatic processes on inhibitory motor control: a Go/Nogo task study. | |
| dc.title.alternative | PLoS One | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1371/journal.pone.0039410 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC] | en_US |
| dc.identifier.pubmed | 22761784 | en_US |
| bordeaux.journal | PLoS ONE | en_US |
| bordeaux.page | e39410 | en_US |
| bordeaux.volume | 7 | en_US |
| bordeaux.hal.laboratories | SANPSY (Sommeil, Addiction, Neuropsychiatrie) - UMR 6033 | en_US |
| bordeaux.issue | 6 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.identifier.funderID | Agence Nationale de la Recherche | en_US |
| bordeaux.import.source | pubmed | |
| hal.identifier | hal-04321661 | |
| hal.version | 1 | |
| hal.date.transferred | 2023-12-04T15:01:10Z | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | true | |
| workflow.import.source | pubmed | |
| dc.rights.cc | CC BY | en_US |
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