AUBERON, Florence; OLATUNJI, Opeyemi Joshua; WAFFO-TEGUO, Pierre; OLATUNDE, Oladipupo Odunayo; SINGH, Sudarshan; BONTÉ, Frédéric; MÉRILLON, Jean-Michel; LOBSTEIN, Annelise

doi:10.1016/j.phytochem.2022.113504

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AUBERON, Florence

OLATUNJI, Opeyemi Joshua

WAFFO-TEGUO, Pierre
Unité de Recherche Œnologie [Villenave d'Ornon] [OENO]

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Phytochemistry. 2023-02, vol. 206, p. 113504

Résumé en anglais

Phytochemical investigation of the underground parts of Arundina graminifolia D.Don Hochr was conducted leading to the isolation of nine new glucosyloxybenzyl 2R-benzylmalate and two new glucosyloxybenzyl 2R-isobutylmalate derivatives. The compounds were purified using chromatographic techniques and their structures were deduced based on spectroscopic techniques including nuclear magnetic resonance and high-resolution mass spectrometry as well as comparing with previous literature. The antioxidant activities of the isolated compounds were also evaluated. The compounds showed potent antioxidant activities in the ABTS radical scavenging, DPPH radical scavenging and FRAP activities. Furthermore, the isolated compounds were observed to exert minimal cytotoxic effects against RAW 264.7 cell, suggesting biocompatibility as well as cytoprotective effects against hydrogen peroxide induced cell toxicity.< Réduire

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Arundina graminifolia D.Don Hochr

Orchidaceae

Glucosyloxybenzyl 2R-benzylmalate derivatives

Glucosyloxybenzyl 2R-isobutylmalate derivatives

Arundinosides I-IX

Graminifolosides A-B

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Arundinosides I-IX and graminifolosides A-B: 2R-benzylmalate and 2R-isobutylmalates derivatives from Arundina graminifolia (D.Don) Hochr. with antioxidant, cytocompatibility and cytoprotective properties

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