On-chip in-situ observations of crystallization events under supercritical CO2
ERCICEK, Fatma
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Chimie et Biologie des Membranes et des Nanoobjets [CBMN]
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Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Chimie et Biologie des Membranes et des Nanoobjets [CBMN]
ERCICEK, Fatma
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Chimie et Biologie des Membranes et des Nanoobjets [CBMN]
< Réduire
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Chimie et Biologie des Membranes et des Nanoobjets [CBMN]
Langue
en
Communication dans un congrès
Ce document a été publié dans
Proceedings 13 th International Symposium on Supercritical Fluids (ISSF), Proceedings 13 th International Symposium on Supercritical Fluids (ISSF), 2022-05-15, Montréal. 2022p. 2 pages
International Society for the Advancement of Supercritical Fluids
Résumé en anglais
Crystallization represents a key unit operation in separation and purification processes in the pharmaceutical industry, about 90% of active pharmaceutical ingredients (API) being obtained by this technique1. Most APIs are ...Lire la suite >
Crystallization represents a key unit operation in separation and purification processes in the pharmaceutical industry, about 90% of active pharmaceutical ingredients (API) being obtained by this technique1. Most APIs are chiral and poorly soluble in water and therefore have a low bioavailability. Understanding crystallization process can help to obtain products with desired properties. The challenge for industries is to be able to produce directly highly water soluble and/or enantiopure drugs without going through several purification steps, which are costly, solvent and time consuming...< Réduire
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