Comparative constraint‐based modelling of fruit development across species highlights nitrogen metabolism in the growth‐defence trade‐off
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| hal.structure.identifier | Plateforme Bordeaux Metabolome | |
| dc.contributor.author | COLOMBIE, Sophie | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| hal.structure.identifier | Plateforme Bordeaux Metabolome | |
| dc.contributor.author | PRIGENT, Sylvain | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| hal.structure.identifier | Plateforme Bordeaux Metabolome | |
| dc.contributor.author | CASSAN, Cédric | |
| hal.structure.identifier | Ecophysiologie et Génomique Fonctionnelle de la Vigne [UMR EGFV] | |
| dc.contributor.author | HILBERT, Ghislaine
IDREF: 075026201 | |
| hal.structure.identifier | Ecophysiologie et Génomique Fonctionnelle de la Vigne [UMR EGFV] | |
| dc.contributor.author | RENAUD, Christel | |
| hal.structure.identifier | Università degli studi della Campania "Luigi Vanvitelli" = University of the Study of Campania Luigi Vanvitelli | |
| dc.contributor.author | DELL'AVERSANA, Emilia | |
| hal.structure.identifier | Università degli studi della Campania "Luigi Vanvitelli" = University of the Study of Campania Luigi Vanvitelli | |
| dc.contributor.author | CARILLO, Petronia | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| hal.structure.identifier | Plateforme Bordeaux Metabolome | |
| dc.contributor.author | MOING, Annick | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| dc.contributor.author | BEAUMONT, Chloé | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| dc.contributor.author | BEAUVOIT, Bertrand | |
| hal.structure.identifier | The University of Queensland [UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations]] | |
| dc.contributor.author | MCCUBBIN, Tim | |
| hal.structure.identifier | The University of Queensland [UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations]] | |
| dc.contributor.author | NIELSEN, Lars | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| hal.structure.identifier | Plateforme Bordeaux Metabolome | |
| dc.contributor.author | GIBON, Yves | |
| dc.date.issued | 2023-08-02 | |
| dc.identifier.issn | 0960-7412 | |
| dc.description.abstractEn | Although primary metabolism is well conserved across species, it is useful to explore the specificity of its network to assess the extent to which some pathways may contribute to particular outcomes. Constraintbased metabolic modelling is an established framework for predicting metabolic fluxes and phenotypes and helps to explore how the plant metabolic network delivers specific outcomes from temporal series. After describing the main physiological traits during fruit development, we confirmed the correlations between fruit relative growth rate (RGR), protein content and time to maturity. Then a constraint-based method is applied to a panel of eight fruit species with a knowledge-based metabolic model of heterotrophic cells describing a generic metabolic network of primary metabolism. The metabolic fluxes are estimated by constraining the model using a large set of metabolites and compounds quantified throughout fruit development. Multivariate analyses showed a clear common pattern of flux distribution during fruit development with differences between fast-and slow-growing fruits. Only the latter fruits mobilise the tricarboxylic acid cycle in addition to glycolysis, leading to a higher rate of respiration. More surprisingly, to balance nitrogen, the model suggests, on the one hand, nitrogen uptake by nitrate reductase to support a high RGR at early stages of cucumber and, on the other hand, the accumulation of alkaloids during ripening of pepper and eggplant. Finally, building virtual fruits by combining 12 biomass compounds shows that the growthdefence trade-off is supported mainly by cell wall synthesis for fast-growing fruits and by total polyphenols accumulation for slow-growing fruits. | |
| dc.description.sponsorship | Modélisation intégrative du fruit pour un système de sélection unifié | |
| dc.description.sponsorship | Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation | |
| dc.description.sponsorship | Centre français de phénomique végétale - ANR-11-INBS-0012 | |
| dc.language.iso | en | |
| dc.publisher | Wiley | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/ | |
| dc.subject.en | constraint-based modelling | |
| dc.subject.en | metabolic fluxes | |
| dc.subject.en | fruit comparison | |
| dc.subject.en | fruit development | |
| dc.subject.en | primary metabolism | |
| dc.subject.en | nitrogen and carbon metabolisms | |
| dc.subject.en | multi-species | |
| dc.title.en | Comparative constraint‐based modelling of fruit development across species highlights nitrogen metabolism in the growth‐defence trade‐off | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1111/tpj.16409 | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Biologie végétale | |
| dc.subject.hal | Sciences de l'environnement/Biodiversité et Ecologie | |
| bordeaux.journal | Plant Journal | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-04185814 | |
| hal.version | 1 | |
| hal.popular | non | |
| hal.audience | Internationale | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-04185814v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Plant%20Journal&rft.date=2023-08-02&rft.eissn=0960-7412&rft.issn=0960-7412&rft.au=COLOMBIE,%20Sophie&PRIGENT,%20Sylvain&CASSAN,%20C%C3%A9dric&HILBERT,%20Ghislaine&RENAUD,%20Christel&rft.genre=article |
