LE GRAND, Fabienne; KRAFFE, Edouard; DE MONTAUDOUIN, Xavier; VILLALBA, Antonio; MARTY, Yanic; SOUDANT, Philippe

doi:10.1016/j.jip.2010.01.011

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LE GRAND, Fabienne

KRAFFE, Edouard

DE MONTAUDOUIN, Xavier

Environnements et Paléoenvironnements OCéaniques [EPOC]

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Journal of Invertebrate Pathology. 2010-01-01, vol. 104, n° 2, p. 110-118

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The present report presents the first evidence of disseminated neoplasia (DN) in cockles Cerastoderma edule from Arcachon Bay (France). Aneuploidy of neoplastic cells allowed the use of flow cytometry (FCM) to diagnose and stage DN. A 1 year survey (2007) of the prevalence and intensity (% of aneuploid circulating cells in neoplastic cockles) was conducted. Prevalences ranged from 2.2% (June) to 13.6% (May), and disease intensity ranged from 18.7% (June) to 95.5% (September). These percentages were not correlated with seawater temperature, but rather showed unexplained oscillations over the year. Prevalence and intensity of DN were higher in cockles found at the surface of sediment compared to those buried normally (11.8% vs. 6.7% and 53.0% vs. 40.6%, respectively, p< Réduire

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Prevalence, intensity, and aneuploidy patterns of disseminated neoplasia in cockles (Cerastoderma edule) from Arcachon Bay: Seasonal variation and position in sediment

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