TUCK, Michael; GRELARD, Florent; BLANC, Landry; DESBENOIT, Nicolas

doi:10.3389/fchem.2022.904688

Chimie et Biologie des Membranes et des Nanoobjets [CBMN]

GRELARD, Florent
Chimie et Biologie des Membranes et des Nanoobjets [CBMN]

BLANC, Landry

Chimie et Biologie des Membranes et des Nanoobjets [CBMN]

Langue

Article de revue

Ce document a été publié dans

Frontiers in Chemistry. 2022-05-09, vol. 10

Résumé en anglais

Multimodal imaging is a powerful strategy for combining information from multiple images. It involves several fields in the acquisition, processing and interpretation of images. As multimodal imaging is a vast subject area with various combinations of imaging techniques, it has been extensively reviewed. Here we focus on Matrix-assisted Laser Desorption Ionization Mass Spectrometry Imaging (MALDI-MSI) coupling other imaging modalities in multimodal approaches. While MALDI-MS images convey a substantial amount of chemical information, they are not readily informative about the morphological nature of the tissue. By providing a supplementary modality, MALDI-MS images can be more informative and better reflect the nature of the tissue. In this mini review, we emphasize the analytical and computational strategies to address multimodal MALDI-MSI.< Réduire

Mots clés en anglais

MALDI mass spectrometry imaging

Multimodal imaging

Analytical strategy

Computational strategy

Biological applications

URI

https://oskar-bordeaux.fr/handle/20.500.12278/182243

DOI

http://dx.doi.org/10.3389/fchem.2022.904688

Project ANR

Imagerie multimodale combinant la spectroscopie Raman et la spectrométrie de masse appliquée à la tuberculose - ANR-19-CE29-0010

Unités de recherche

CBMN : Chimie & de Biologie des Membranes & des Nano-objets - UMR 5248

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MALDI-MSI Towards Multimodal Imaging: Challenges and Perspectives