MALDI-MSI Towards Multimodal Imaging: Challenges and Perspectives
Idioma
EN
Article de revue
Este ítem está publicado en
Frontiers in Chemistry. 2022-05-09, vol. 10
Resumen en inglés
Multimodal imaging is a powerful strategy for combining information from multiple images. It involves several fields in the acquisition, processing and interpretation of images. As multimodal imaging is a vast subject area ...Leer más >
Multimodal imaging is a powerful strategy for combining information from multiple images. It involves several fields in the acquisition, processing and interpretation of images. As multimodal imaging is a vast subject area with various combinations of imaging techniques, it has been extensively reviewed. Here we focus on Matrix-assisted Laser Desorption Ionization Mass Spectrometry Imaging (MALDI-MSI) coupling other imaging modalities in multimodal approaches. While MALDI-MS images convey a substantial amount of chemical information, they are not readily informative about the morphological nature of the tissue. By providing a supplementary modality, MALDI-MS images can be more informative and better reflect the nature of the tissue. In this mini review, we emphasize the analytical and computational strategies to address multimodal MALDI-MSI.< Leer menos
Palabras clave en inglés
MALDI mass spectrometry imaging
Multimodal imaging
Analytical strategy
Computational strategy
Biological applications
Proyecto ANR
Imagerie multimodale combinant la spectroscopie Raman et la spectrométrie de masse appliquée à la tuberculose - ANR-19-CE29-0010
Centros de investigación