MALDI-MSI Towards Multimodal Imaging: Challenges and Perspectives
Language
EN
Article de revue
This item was published in
Frontiers in Chemistry. 2022-05-09, vol. 10
English Abstract
Multimodal imaging is a powerful strategy for combining information from multiple images. It involves several fields in the acquisition, processing and interpretation of images. As multimodal imaging is a vast subject area ...Read more >
Multimodal imaging is a powerful strategy for combining information from multiple images. It involves several fields in the acquisition, processing and interpretation of images. As multimodal imaging is a vast subject area with various combinations of imaging techniques, it has been extensively reviewed. Here we focus on Matrix-assisted Laser Desorption Ionization Mass Spectrometry Imaging (MALDI-MSI) coupling other imaging modalities in multimodal approaches. While MALDI-MS images convey a substantial amount of chemical information, they are not readily informative about the morphological nature of the tissue. By providing a supplementary modality, MALDI-MS images can be more informative and better reflect the nature of the tissue. In this mini review, we emphasize the analytical and computational strategies to address multimodal MALDI-MSI.Read less <
English Keywords
MALDI mass spectrometry imaging
Multimodal imaging
Analytical strategy
Computational strategy
Biological applications
ANR Project
Imagerie multimodale combinant la spectroscopie Raman et la spectrométrie de masse appliquée à la tuberculose - ANR-19-CE29-0010