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dc.rights.licenseopenen_US
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorARINI, Adeline
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorVENEL, Zelie
dc.contributor.authorTABUTEAU, Hervé
dc.contributor.authorGIGAULT, Julien
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorBAUDRIMONT, Magalie
IDREF: 105696722
dc.date.accessioned2023-05-17T08:04:00Z
dc.date.available2023-05-17T08:04:00Z
dc.date.issued2022-08-15
dc.identifier.issn0304-3894en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/182184
dc.description.abstractEnThis study assessed the effects of nanoplastics (NPs) using for the very first time microfluidic devices (chip) mimicking transition waters. Three kinds of NPs were tested: crushed NPs from polystyrene pellets (NP-PS), or from Guadeloupe beaches (NP-G); and latex PS (PSL-COOH). The eluted fractions from the microfluidic device showed a low aggregation of NPs. They remained stable over time in the exposure media, with a stabilization of NPs of small sizes (< 500 nm). These chips were thus used for the toxicological assessment of NPs on swamp oysters, Isognomon alatus. Oysters were exposed for 7 days to the chip elution fraction of either NP-G, NP-PS or PSL-COOH (0.34–333 µg.L−1). Gene transcription analyses showed that the tested NPs triggered responses on genes involved in endocytosis, mitochondrial metabolism disruption, oxidative stress, DNA repair, and detoxification. Highest responses were observed after NP-G exposure at low concentrations (1 µg.L−1), as they are originated from the natural environment and accumulated contaminants, enhancing toxicological effects. As salinity influences aggregation and then the bioavailability of NPs, our results demonstrated the importance of using microfluidic devices for ecotoxicological studies on swamp or estuarine species.
dc.description.sponsorshipNanoparticules de plastiques dans l'environnement: source, impact et prédiction - ANR-17-CE34-0008en_US
dc.language.isoENen_US
dc.title.enEarly molecular responses of mangrove oysters to nanoplastics using a microfluidic device to mimic environmental exposure
dc.title.alternativeJournal of Hazardous Materialsen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jhazmat.2022.129283en_US
dc.subject.halSciences de l'environnementen_US
bordeaux.journalJournal of Hazardous Materialsen_US
bordeaux.volume436en_US
bordeaux.hal.laboratoriesEPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.teamEAen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.jtitle=Journal%20of%20Hazardous%20Materials&amp;rft.date=2022-08-15&amp;rft.volume=436&amp;rft.eissn=0304-3894&amp;rft.issn=0304-3894&amp;rft.au=ARINI,%20Adeline&amp;VENEL,%20Zelie&amp;TABUTEAU,%20Herv%C3%A9&amp;GIGAULT,%20Julien&amp;BAUDRIMONT,%20Magalie&amp;rft.genre=article


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