Afficher la notice abrégée

Detecting fine and elaborate movements with piezo sensors, from heartbeat to the temporal organization of behavior

dc.rights.licenseopenen_US
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorCARRENO-MUNOZ, Maria Isabel
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorMEDRANO, Maria-Carmen
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorLEINEKUGEL, Thomas
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorBOMPART, Maelys
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorMARTINS, Fabienne
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorSUBASHI, Enejda
hal.structure.identifierInterdisciplinary Institute for Neuroscience [Bordeaux] [IINS]
dc.contributor.authorABY, Franck
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorFRICK, Andreas
hal.structure.identifierInterdisciplinary Institute for Neuroscience [Bordeaux] [IINS]
dc.contributor.authorLANDRY, Marc
hal.structure.identifierUniversity of the Basque Country = Euskal Herriko Unibertsitatea [UPV / EHU]
dc.contributor.authorGRANA, Manuel
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorLEINEKUGEL, Xavier
dc.date.accessioned2023-01-10T17:31:39Z
dc.date.available2023-01-10T17:31:39Z
dc.date.created2020-08-07
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/171650
dc.description.abstractEnBehavioral phenotyping devices have been successfully used to build ethograms, but many aspects of behavior remain out of reach of available phenotyping systems. We now report on a novel device, which consists in an open-field platform resting on highly sensitive piezoelectric (electromechanical) pressure-sensors, with which we could detect the slightest movements (up to individual heart beats during rest) from freely moving rats and mice. The combination with video recordings and signal analysis based on time-frequency decomposition, clustering, and machine learning algorithms provided non-invasive access to previously overlooked behavioral components. The detection of shaking/shivering provided an original readout of fear, distinct from but complementary to behavioral freezing. Analyzing the dynamics of momentum in locomotion and grooming allowed to identify the signature of gait and neurodevelopmental pathological phenotypes. We believe that this device represents a significant progress and offers new opportunities for the awaited advance of behavioral phenotyping. © 2021, The Author(s), under exclusive licence to American College of Neuropsychopharmacology.
dc.description.sponsorshipBordeaux Region Aquitaine Initiative for Neuroscience - ANR-10-LABX-0043en_US
dc.description.sponsorshipInitiative d'excellence de l'Université de Bordeaux - ANR-10-IDEX-0003en_US
dc.language.isoENen_US
dc.subject.enAnimals
dc.subject.enFear Grooming
dc.subject.enHeart Rate
dc.subject.enMachine Learning
dc.subject.enMice Movement
dc.subject.enRats
dc.title.enDetecting fine and elaborate movements with piezo sensors, from heartbeat to the temporal organization of behavior
dc.title.alternativeNeuropsychopharmacologyen_US
dc.typeDocument de travail - Pré-publicationen_US
dc.identifier.doi10.1038/s41386-021-01217-wen_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed34764433en_US
bordeaux.page933-943en_US
bordeaux.hal.laboratoriesNeurocentre Magendie - U1215en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCNRS
bordeaux.teamPlasticité Corticaleen_US
bordeaux.identifier.funderIDConseil Régional Aquitaineen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.spage=933-943&rft.epage=933-943&rft.au=CARRENO-MUNOZ,%20Maria%20Isabel&MEDRANO,%20Maria-Carmen&LEINEKUGEL,%20Thomas&BOMPART,%20Maelys&MARTINS,%20Fabienne&rft.genre=preprint


Fichier(s) constituant ce document

Thumbnail
Nom:
MAGENDIE_Neuropsychopharmacolo ...
Taille:
6.580Mo
Format:
PDF
Voir/Ouvrir

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée