In vivo role of capsular polysaccharide in <em>Mycoplasma mycoides</em>
JORES, Joerg
Universität Bern / University of Bern [UNIBE]
International Livestock Research Institute [CGIAR, Nairobi] [ILRI]
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Universität Bern / University of Bern [UNIBE]
International Livestock Research Institute [CGIAR, Nairobi] [ILRI]
JORES, Joerg
Universität Bern / University of Bern [UNIBE]
International Livestock Research Institute [CGIAR, Nairobi] [ILRI]
Universität Bern / University of Bern [UNIBE]
International Livestock Research Institute [CGIAR, Nairobi] [ILRI]
SACCHINI, Flavio
Universität Bern / University of Bern [UNIBE]
International Livestock Research Institute [CGIAR, Nairobi] [ILRI]
< Reduce
Universität Bern / University of Bern [UNIBE]
International Livestock Research Institute [CGIAR, Nairobi] [ILRI]
Language
en
Article de revue
This item was published in
Journal of Infectious Diseases. 2019, vol. 219, n° 10, p. 1559-1563
Oxford University Press
English Abstract
Capsular polysaccharides have been confirmed to be an important virulence trait in many different Gram-positive and Gram-negative bacteria. Similarly, they are proposed to be virulence traits in minimal Mycoplasma that ...Read more >
Capsular polysaccharides have been confirmed to be an important virulence trait in many different Gram-positive and Gram-negative bacteria. Similarly, they are proposed to be virulence traits in minimal Mycoplasma that cause disease in humans and animals. In this study, goats were infected with the caprine pathogen Mycoplasma mycoides subsp. capri or an engineered mutant lacking the capsular polysaccharide, galactofuranose. Goats infected with the mutant strain showed only transient fever. In contrast, five out of eight goats infected with the parental strain reached endpoint criteria after infection. This work confirms that galactofuranose is a virulence factor in Mycoplasma mycoides.Read less <
Keywords
M. mycoides subsp. capri
galactofuranose
vaccine
English Keywords
Mycoplasma mycoides
carbohydrate
glycan
virulence factor
CPS
Origin
Hal importedCollections