Finding and identifying the viral needle in the metagenomic haystack: Trends and Challenges
| hal.structure.identifier | Biothérapies des maladies génétiques et cancers | |
| hal.structure.identifier | Centre de Bioinformatique de Bordeaux [CBIB] | |
| dc.contributor.author | SOUEIDAN, Hayssam | |
| hal.structure.identifier | Centre de Bioinformatique de Bordeaux [CBIB] | |
| hal.structure.identifier | Laboratoire Bordelais de Recherche en Informatique [LaBRI] | |
| dc.contributor.author | SCHMITT, Louise-Amélie | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| dc.contributor.author | CANDRESSE, Thierry | |
| hal.structure.identifier | Centre de Bioinformatique de Bordeaux [CBIB] | |
| hal.structure.identifier | Laboratoire Bordelais de Recherche en Informatique [LaBRI] | |
| dc.contributor.author | NIKOLSKI, Macha | |
| dc.date.issued | 2014-12-05 | |
| dc.identifier.issn | 1664-302X | |
| dc.description.abstractEn | Collectively, viruses have the greatest genetic diversity on Earth, occupy extremely varied niches and are likely able to infect all living organisms. Viral infections are an important issue for human health and cause considerable economic losses when agriculturally important crops or husbandry animals are infected. The advent of metagenomics has provided a precious tool to study viruses by sampling them in natural environments and identifying the genomic composition of a sample. However, reaching a clear recognition and taxonomic assignment of the identified viruses has been hampered by the computational difficulty of these problems. In this perspective paper we examine the trends in current research for the identification of viral sequences in a metagenomic sample, pinpoint the intrinsic computational difficulties for the identification of novel viral sequences within metagenomic samples, and suggest possible avenues to overcome them. | |
| dc.language.iso | en | |
| dc.publisher | Frontiers Media | |
| dc.rights.uri | http://creativecommons.org/licenses/by/ | |
| dc.subject.en | Taxonomic assignment | |
| dc.subject.en | host-pathogen interactions | |
| dc.subject.en | NGS | |
| dc.subject.en | virome | |
| dc.subject.en | microbial metagenomics | |
| dc.title.en | Finding and identifying the viral needle in the metagenomic haystack: Trends and Challenges | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.3389/fmicb.2014.00739 | |
| dc.subject.hal | Informatique [cs]/Bio-informatique [q-bio.QM] | |
| dc.subject.hal | Informatique [cs]/Apprentissage [cs.LG] | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Biodiversité/Systématique, phylogénie et taxonomie | |
| bordeaux.journal | Frontiers in Microbiology | |
| bordeaux.page | 5:739 | |
| bordeaux.volume | 5 | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-01100888 | |
| hal.version | 1 | |
| hal.popular | non | |
| hal.audience | Internationale | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-01100888v1 | |
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