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Bioguided isolation, characterization, and biotransformation by Fusarium verticillioides of maize kernel compounds that inhibit fumonisin production

hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
dc.contributor.authorATANASOVA-PENICHON, Vessela
hal.structure.identifierBiologie du fruit et pathologie [BFP]
hal.structure.identifierInstitut National de la Recherche Agronomique [INRA]
dc.contributor.authorBERNILLON, Stéphane
hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
dc.contributor.authorMARCHEGAY, Gisele
hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
dc.contributor.authorLORNAC, Aurélia
hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
dc.contributor.authorPINSON-GADAIS, Laetitia
hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
dc.contributor.authorPONTS, Nadia
hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
dc.contributor.authorZEHRAOUI, Enric
hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
hal.structure.identifierCentre National de la Recherche Scientifique [CNRS]
dc.contributor.authorBARREAU, Christian
hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
dc.contributor.authorRICHARD-FORGET, Florence
dc.date.issued2014
dc.identifier.issn0894-0282
dc.description.abstractEnFusarium verticillioides infects maize ears, causing ear rot disease and contamination of grain with fumonisin mycotoxins. This contamination can be reduced by the presence of bioactive compounds in kernels that are able to inhibit fumonisin biosynthesis. To identify such compounds, we used kernels from a maize genotype with moderate susceptibility to F. verticillioides, harvested at the milk-dough stage (i.e., when fumonisin production initiates in planta), and applied a bioguided fractionation approach. Chlorogenic acid was the most abundant compound in the purified active fraction and its contribution to fumonisin inhibitory activity was up to 70%. Moreover, using a set of maize genotypes with different levels of susceptibility, chlorogenic acid was shown to be significantly higher in immature kernels of the moderately susceptible group. Altogether, our data indicate that chlorogenic acid may considerably contribute to either maize resistance to Fusarium ear rot, fumonisin accumulation, or both. We further investigated the mechanisms involved in the inhibition of fumonisin production by chlorogenic acid and one of its hydrolyzed products, caffeic acid, by following their metabolic fate in supplemented F. verticillioides broths. Our data indicate that F. verticillioides was able to biotransform these phenolic compounds and that the resulting products can contribute to their inhibitory activity.
dc.language.isoen
dc.publisherAmerican Phytopathological Society
dc.title.enBioguided isolation, characterization, and biotransformation by Fusarium verticillioides of maize kernel compounds that inhibit fumonisin production
dc.typeArticle de revue
dc.identifier.doi10.1094/MPMI-04-14-0100-R
dc.subject.halSciences du Vivant [q-bio]
dc.subject.halSciences du Vivant [q-bio]/Biologie végétale
dc.description.sponsorshipEuropePesticide Use-and-risk Reduction in European farming systems with Integrated Pest Management
bordeaux.journalMolecular Plant-Microbe Interactions
bordeaux.page1148-1158
bordeaux.volume27
bordeaux.issue10
bordeaux.peerReviewedoui
hal.identifierhal-02633252
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-02633252v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Molecular%20Plant-Microbe%20Interactions&rft.date=2014&rft.volume=27&rft.issue=10&rft.spage=1148-1158&rft.epage=1148-1158&rft.eissn=0894-0282&rft.issn=0894-0282&rft.au=ATANASOVA-PENICHON,%20Vessela&BERNILLON,%20St%C3%A9phane&MARCHEGAY,%20Gisele&LORNAC,%20Aur%C3%A9lia&PINSON-GADAIS,%20Laetitia&rft.genre=article


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