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hal.structure.identifierJ. Craig Venter Institute [La Jolla, USA] [JCVI]
dc.contributor.authorMONTAGUE, Michael G.
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorLARTIGUE, Carole
hal.structure.identifierJ. Craig Venter Institute [La Jolla, USA] [JCVI]
dc.contributor.authorVASHEE, Sanjay
dc.date.issued2012
dc.identifier.issn0958-1669
dc.description.abstractEnTechnologies to synthetically assemble chromosome sized fragments of DNA as well as to enable making thousands of simultaneous changes to existing genomes are now available. These capacities are collectively termed synthetic genomics. The implications of synthetic genomics extend beyond the limited pathway and gene engineering of the past to include the engineering or whole metabolisms, regulatory networks, and even ecosystems. However, in order for those potentials to be met, certain limitations and barriers must be overcome. These barriers no longer include DNA modification and assembly, but instead are based in the limited organisms that many synthetic genomics methods function in, and the limited software for designing custom genomic sequences.
dc.language.isoen
dc.publisherElsevier
dc.title.enSynthetic genomics: potential and limitations.
dc.typeArticle de revue
dc.identifier.doi10.1016/j.copbio.2012.01.014
dc.subject.halSciences du Vivant [q-bio]/Biologie animale
bordeaux.journalCurrent Opinion in Biotechnology
bordeaux.page659-665
bordeaux.volume23
bordeaux.issue5
bordeaux.peerReviewedoui
hal.identifierhal-02648903
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-02648903v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Current%20Opinion%20in%20Biotechnology&rft.date=2012&rft.volume=23&rft.issue=5&rft.spage=659-665&rft.epage=659-665&rft.eissn=0958-1669&rft.issn=0958-1669&rft.au=MONTAGUE,%20Michael%20G.&LARTIGUE,%20Carole&VASHEE,%20Sanjay&rft.genre=article


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