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MeRy-B: a web knowledgebase for the storage, visualization, analysis and annotation of plant 1H-NMR metabolomic profiles

hal.structure.identifierCentre de Bioinformatique de Bordeaux [CBIB]
dc.contributor.authorFERRY-DUMAZET, H.
hal.structure.identifierCentre de Bioinformatique de Bordeaux [CBIB]
dc.contributor.authorGIL, L.
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorDEBORDE, C.
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorMOING, Annick
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorBERNILLON, Stéphane
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorROLIN, D.
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
dc.contributor.authorNIKOLSKI, Macha
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
dc.contributor.authorDE DARUVAR, Antoine
hal.structure.identifierCentre de Bioinformatique de Bordeaux [CBIB]
dc.contributor.authorJACOB, D.
dc.date.issued2011
dc.identifier.issn1471-2229
dc.description.abstractEnBackground Improvements in the techniques for metabolomics analyses and growing interest in metabolomic approaches are resulting in the generation of increasing numbers of metabolomic profiles. Platforms are required for profile management, as a function of experimental design, and for metabolite identification, to facilitate the mining of the corresponding data. Various databases have been created, including organism-specific knowledgebases and analytical technique-specific spectral databases. However, there is currently no platform meeting the requirements for both profile management and metabolite identification for nuclear magnetic resonance (NMR) experiments. Description MeRy-B, the first platform for plant 1H-NMR metabolomic profiles, is designed (i) to provide a knowledgebase of curated plant profiles and metabolites obtained by NMR, together with the corresponding experimental and analytical metadata, (ii) for queries and visualization of the data, (iii) to discriminate between profiles with spectrum visualization tools and statistical analysis, (iv) to facilitate compound identification. It contains lists of plant metabolites and unknown compounds, with information about experimental conditions, the factors studied and metabolite concentrations for several plant species, compiled from more than one thousand annotated NMR profiles for various organs or tissues. Conclusion MeRy-B manages all the data generated by NMR-based plant metabolomics experiments, from description of the biological source to identification of the metabolites and determinations of their concentrations. It is the first database allowing the display and overlay of NMR metabolomic profiles selected through queries on data or metadata. MeRy-B is available from http://www.cbib.u-bordeaux2.fr/MERYB/index.php
dc.language.isoen
dc.publisherBioMed Central
dc.title.enMeRy-B: a web knowledgebase for the storage, visualization, analysis and annotation of plant 1H-NMR metabolomic profiles
dc.typeArticle de revue
dc.subject.halInformatique [cs]/Bio-informatique [q-bio.QM]
dc.subject.halSciences du Vivant [q-bio]/Bio-Informatique, Biologie Systémique [q-bio.QM]
bordeaux.journalBMC Plant Biology
bordeaux.page10.1186/1471-2229-11-104
bordeaux.volume11:104
bordeaux.peerReviewedoui
hal.identifierhal-00648167
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00648167v1
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