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Spectroscopical study of bacteriopurpurinimide-naphthalimide conjugates for fluorescent diagnostics and photodynamic therapy

hal.structure.identifierA. N. Nesmeyanov Institute of Organoelement Compounds [INEOS]
dc.contributor.authorPANCHENKO, Pavel A.
hal.structure.identifierA. N. Nesmeyanov Institute of Organoelement Compounds [INEOS]
dc.contributor.authorSERGEEVA, Antonina N.
hal.structure.identifierA. N. Nesmeyanov Institute of Organoelement Compounds [INEOS]
dc.contributor.authorFEDOROVA, Olga A.
hal.structure.identifierA. N. Nesmeyanov Institute of Organoelement Compounds [INEOS]
dc.contributor.authorFEDOROV, Yuri V.
hal.structure.identifierLMSU of Fine Chemical Technologies
dc.contributor.authorRESHETNIKOV, Roman I.
hal.structure.identifierLMSU of Fine Chemical Technologies
dc.contributor.authorSCHELKUNOVA, Anastasiya E.
hal.structure.identifierLMSU of Fine Chemical Technologies
dc.contributor.authorGRIN, Michail A.
hal.structure.identifierLMSU of Fine Chemical Technologies
dc.contributor.authorMIRONOV, Andrey F.
hal.structure.identifierLaboratoire Ondes et Matière d'Aquitaine [LOMA]
dc.contributor.authorJONUSAUSKAS, Gediminas
dc.date.created2013-12-18
dc.date.issued2014-04-05
dc.identifier.issn1011-1344
dc.description.abstractEnTwo novel bis(chromophoric) dyads ABPI-NI1 and ABPI-NI2 containing 1,8-naphthalimide and bacteriopurpurinimide units linked by p-phenylene-methylene (ABPI-NI1) and pentamethylene (ABPI-NI2) spacers were prepared to test their ability to be used in the design of effective agents for both photodynamic therapy (PDT) and fluorescent tumor imaging. Photophysical studies revealed that the emission from the naphthalimide chromophore in both conjugates was partially quenched due to resonance energy transfer between the photoactive components. Compound ABPI-NI2 with more sterically flexible oligomethylene group demonstrated higher fluorescence intensity as compared with that for ABPI-NI1.
dc.language.isoen
dc.publisherElsevier
dc.rights.urihttp://creativecommons.org/licenses/by-nc/
dc.subject.en8-Naphthalimide
dc.subject.enConjugate
dc.subject.enBacteriopurpurinimide
dc.subject.enPhotodynamic therapy
dc.subject.enResonance energy transfer
dc.subject.enFluorescence imaging
dc.subject.enPM6 semiempirical calculations
dc.title.enSpectroscopical study of bacteriopurpurinimide-naphthalimide conjugates for fluorescent diagnostics and photodynamic therapy
dc.typeArticle de revue
dc.identifier.doi10.1016/j.jphotobiol.2014.03.008
dc.subject.halChimie/Chimie analytique
bordeaux.journalJournal of Photochemistry and Photobiology B: Biology
bordeaux.page140-144
bordeaux.volume133
bordeaux.peerReviewedoui
hal.identifierhal-00978356
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00978356v1
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