Physicochemical Stability of Solid Dispersions of Enantiomeric or Racemic Ibuprofen in Stearic Acid
Idioma
en
Article de revue
Este ítem está publicado en
Journal of Pharmaceutical Sciences. 2011, vol. 100, n° 12, p. 5235-5243
Wiley
Resumen en inglés
The aim of this study was to investigate the solid dispersion phase behavior of s- or rs-ibuprofen in stearic acid. By means of thermal analysis, we have demonstrated the total immiscibility, in solid state, of the ...Leer más >
Palabras clave en inglés
miscibility
melt-recrystallization process
solubility
polymorphism
solid-state stability
phase diagram
drug-excipient interactions
thermal analysis
X-ray powder diffraction
drug–excipient interactions