Numerical studies on the effect of electric pulses on an egg-shaped cell with a spherical nucleus
Langue
en
Rapport
Ce document a été publié dans
2010-04-29p. 21
Résumé en anglais
In this paper, we study the influence of nanosecond electrical pulses on the phenomena arising in a biological cell model composed of a nucleus embedded in a cytoplasm, both entities being surrounded by a thin resistive ...Lire la suite >
In this paper, we study the influence of nanosecond electrical pulses on the phenomena arising in a biological cell model composed of a nucleus embedded in a cytoplasm, both entities being surrounded by a thin resistive membrane. The time-harmonic and the time-transient equations of the electric potential are presented, and accurate approximations of these equations are given, that avoid to mesh the thin resistive membranes. Numerical formulations of the partial differential equations are derived and simulations are performed in order to study the sensitivity of an eukaryotic cell to the orientation, the amplitude and the duration of the applied electric pulses.< Réduire
Mots clés en anglais
Electroporation modelling
Finite element methods
Variational formulation
Electric potential
Project ANR
Modélisation multi-échelle de l'électroporation validée par les expériences - ANR-11-BS01-0006
Origine
Importé de halUnités de recherche