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Towards a versatile platform based on magnetic nanoparticles for in vivo applications

hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorDUGUET, Etienne
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorVASSEUR, Sébastien
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorMORNET, Stéphane
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorGOGLIO, Graziella
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorDEMOURGUES, Alain
hal.structure.identifierInstitut des Sciences Chimiques de Rennes [ISCR]
dc.contributor.authorGRASSET, Fabien
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorPORTIER, Josik
hal.structure.identifierInstitute of Physics
dc.contributor.authorVEVERKA, P.
hal.structure.identifierInstitute of Physics
dc.contributor.authorPOLLERT, E.
dc.date.issued2006
dc.identifier.issn0250-4707
dc.description.abstractEnMagnetic nanoparticles have attracted wide attention because of their usefulness as contrast agents for magnetic resonance imaging (MRI) or colloidal mediators for cancer magnetic hyperthermia. This paper examines these in vivo applications through an understanding of the problems involved and the current and future possibilities for resolving them. A special emphasis is made on magnetic nanoparticle requirements from a physical viewpoint, the factors affecting their biodistribution and the solutions envisaged for enhancing their half-life in the blood compartment and targeting tumour cells. Then, our synthesis strategies are presented and focused on covalent platforms based on maghemite and dextran and capable to be tailorderivatized by surface molecular chemistry. The opportunity of taking advantage of temperature-dependence of magnetic properties of some complex oxides for controlling the in vivo temperature is also discussed.
dc.language.isoen
dc.publisherIndian Academy of Sciences
dc.title.enTowards a versatile platform based on magnetic nanoparticles for in vivo applications
dc.typeArticle de revue
dc.identifier.doi10.1007/s12034-006-0007-0
dc.subject.halChimie/Matériaux
bordeaux.journalBulletin of Materials Science
bordeaux.pagep. 581-586
bordeaux.volume29
bordeaux.issue6
bordeaux.peerReviewedoui
hal.identifierhal-00119965
hal.version1
hal.popularnon
hal.audienceInternationale
dc.subject.itMagnetic nanoparticle
dc.subject.itSurface functionalization
dc.subject.itIn vivo biodistribution
dc.subject.itMagnetic resonance imaging (MRI)
dc.subject.itMagnetic hyperthermia
dc.subject.itContrast agent
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00119965v1
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