Use of lanthanide-grafted inorganic nanoparticles as effective contrast agents for cellular uptake imaging
LAHITTE, Jean-François
Centre de résonance magnétique des systèmes biologiques [CRMSB]
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Centre de résonance magnétique des systèmes biologiques [CRMSB]
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
MORNET, Stéphane
Imagerie Moléculaire et Nanobiotechnologies - Institut Européen de Chimie et Biologie [IECB]
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Imagerie Moléculaire et Nanobiotechnologies - Institut Européen de Chimie et Biologie [IECB]
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en
Article de revue
Este ítem está publicado en
Bioconjugate Chemistry. 2007, vol. 18, n° 4, p. 1053-1063
American Chemical Society
Resumen en inglés
The improvement of commonly used Gd3+-based MRI agents requires the design of new systems with optimized in ViVo efficacy, pharmacokinetic properties, and specificity. To design these contrast agents, two parameters are ...Leer más >
The improvement of commonly used Gd3+-based MRI agents requires the design of new systems with optimized in ViVo efficacy, pharmacokinetic properties, and specificity. To design these contrast agents, two parameters are usually considered: increasing the number of coordinated water molecules or increasing the rotational correlation time by increasing molecular weight and size...< Leer menos
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