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dc.rights.licenseopenen_US
dc.contributor.authorHUNYOR, A. P.
dc.contributor.authorMERANI, R.
dc.contributor.authorDARBAR, A.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorKOROBELNIK, Jean-Francois
ORCID: 0000-0002-4438-9535
IDREF: 028739272
dc.contributor.authorLANZETTA, P.
dc.contributor.authorOKADA, A. A.
dc.date.accessioned2020-11-17T09:07:19Z
dc.date.available2020-11-17T09:07:19Z
dc.date.issued2018-08
dc.identifier.issn1755-3768 (Electronic) 1755-375X (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/14052
dc.description.abstractEnThere is increasing evidence that topical antibiotics, given before and/or after intravitreal injections, are ineffective in preventing endophthalmitis and are possibly harmful. In addition to the lack of efficacy and increased development of resistant organisms, the use of topical antibiotics adds significantly to the cost of delivering intravitreal therapy. Despite this, in many countries, it is still common practice to use pre- and/or postinjection topical antibiotics. This review outlines the general principles of effective antibiotic prophylaxis, and the evidence regarding topical antibiotic use as a prophylactic measure for endophthalmitis following intravitreal injections. A key distinguishing feature of intravitreal injections from most other invasive procedures is the fact that they are often repeated on multiple occasions to the same eye. Given the lack of evidence to support topical antibiotics as an effective method of prophylaxis for postinjection endophthalmitis, it appears that more widespread education of ophthalmologists is required to avoid continued inappropriate use. Revision of drug labels in some jurisdictions, and amendment of local/professional society guidelines, may be required to assist in achieving this goal. Emphasis should be placed on antisepsis and aseptic technique, which are the major proven methods of endophthalmitis prevention, rather than antibiotics.
dc.language.isoENen_US
dc.subject.enLEHA
dc.title.enTopical antibiotics and intravitreal injections
dc.title.alternativeActa Ophthalmolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1111/aos.13417en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed28440583en_US
bordeaux.journalActa Ophthalmologicaen_US
bordeaux.page435-441en_US
bordeaux.volume96en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue5en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03193085
hal.version1
hal.date.transferred2021-04-08T13:33:12Z
hal.exporttrue
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