Pickering emulsions stabilized by biodegradable dextran-based nanoparticles featuring enzyme responsiveness and co-encapsulation of actives
| dc.rights.license | open | en_US |
| hal.structure.identifier | Team 1 LCPO : Polymerization Catalyses & Engineering | |
| hal.structure.identifier | Centre de Recherche Paul Pascal [CRPP] | |
| dc.contributor.author | MAINGRET, Valentin | |
| hal.structure.identifier | Team 1 LCPO : Polymerization Catalyses & Engineering | |
| hal.structure.identifier | Centre de Recherche Paul Pascal [CRPP] | |
| dc.contributor.author | CHARTIER, Coraline | |
| dc.contributor.author | SIX, Jean-Luc | |
| hal.structure.identifier | Centre de Recherche Paul Pascal [CRPP] | |
| dc.contributor.author | SCHMITT, Veronique | |
| hal.structure.identifier | Team 1 LCPO : Polymerization Catalyses & Engineering | |
| dc.contributor.author | HEROGUEZ, Valerie | |
| dc.date.accessioned | 2022-06-20T07:08:49Z | |
| dc.date.available | 2022-06-20T07:08:49Z | |
| dc.date.issued | 2022 | |
| dc.identifier.issn | 1448617 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/140276 | |
| dc.description.abstractEn | In this study, Pickering emulsions of dodecane and medium chain triglyceride (MCT) oils were stabilized by simply alkylated-dextran nanoparticles. Our findings show that very little of these bio-friendly nanoparticles is necessary to stabilize Pickering emulsions while providing a high time stability (more than a year at 37 °C). As dextran is known to be cleavable by dextranase enzyme, hydrolysis of the nanoparticles in the presence of dextranase could be achieved. This allowed performing on-demand destabilization of Pickering emulsions. Furthermore, two different fluorescent probes were loaded into the stabilizing particles and the oil droplets respectively, providing a proof of concept for co-encapsulation of actives in advanced delivery applications. Additionally, to a conventional fluorescence probe, quinine, an antimalarial drug was also encapsulated into the nanoparticles. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Biodegradation | |
| dc.subject.en | Stimuli-responsiveness | |
| dc.subject.en | Encapsulation | |
| dc.subject.en | Sustainable release | |
| dc.subject.en | Dextranase | |
| dc.subject.en | Fluorescence | |
| dc.title.en | Pickering emulsions stabilized by biodegradable dextran-based nanoparticles featuring enzyme responsiveness and co-encapsulation of actives | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.carbpol.2022.119146 | en_US |
| dc.subject.hal | Chimie/Matériaux | en_US |
| bordeaux.journal | Carbohydrate Polymers | en_US |
| bordeaux.page | 119146 | en_US |
| bordeaux.volume | 284 | en_US |
| bordeaux.hal.laboratories | Centre de Recherche Paul Pascal (CRPP) - UMR 5031 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03699135 | |
| hal.version | 1 | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Carbohydrate%20Polymers&rft.date=2022&rft.volume=284&rft.spage=119146&rft.epage=119146&rft.eissn=1448617&rft.issn=1448617&rft.au=MAINGRET,%20Valentin&CHARTIER,%20Coraline&SIX,%20Jean-Luc&SCHMITT,%20Veronique&HEROGUEZ,%20Valerie&rft.genre=article |
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