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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDAOUD-PINEAU, Frederic
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorCOPPRY, Maider
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorMOORE, Nicholas
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorROGUES, Anne-Marie
dc.date.accessioned2022-06-14T08:28:26Z
dc.date.available2022-06-14T08:28:26Z
dc.date.issued2022-04-28
dc.identifier.issn2076-2607 (Print) 2076-2607 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/140203
dc.description.abstractEnRandomised controlled clinical trials (RCTs) report a lower incidence rate of surgical site infections (SSIs) with triclosan sutures (TSs) compared with non-triclosan sutures (NTSs). Do triclosan sutures modify the microbial diversity of culture-confirmed SSIs (ccSSIs)? If so, this would support the association between TS antimicrobial activity and the SSI incidence rate. This prospective systematic literature review (PROSPERO CRD42019125099) was conducted according to PRISMA. RCTs that compared the incidence of SSIs with TSs and NTSs and reported microbial counts from SSI cultures per suture group were eligible. The microbial species were grouped by genus, and the association between genera and sutures was tested. The pooled relative risk (RR) of ccSSIs was also calculated. Twelve RCTs were eligible. No publication bias was identified. The microorganism count was 180 in 124 SSIs with TSs versus 246 in 199 SSIs with NTSs. No significant difference in microbial diversity was found, but statistical power was low for test results to support or challenge the association between the antimicrobial activity of TSs and the reduced rate of SSIs. The RR of the ccSSIs was significant and consistent with comprehensive meta-analyses. The certainty of the pooled RR was moderate.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enSurgical site infection
dc.subject.enMicroorganisms
dc.subject.enDiversity
dc.subject.enSutures
dc.subject.enTriclosan
dc.subject.enMeta-analysis
dc.title.enDo Triclosan Sutures Modify the Microbial Diversity of Surgical Site Infections? A Systematic Review and Meta-Analysis
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/microorganisms10050927en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed35630370en_US
bordeaux.journalMicroorganismsen_US
bordeaux.page927en_US
bordeaux.volume10en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue5en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamAHEAD_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03696480
hal.version1
hal.date.transferred2022-06-16T06:39:19Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Microorganisms&rft.date=2022-04-28&rft.volume=10&rft.issue=5&rft.spage=927&rft.epage=927&rft.eissn=2076-2607%20(Print)%202076-2607%20(Linking)&rft.issn=2076-2607%20(Print)%202076-2607%20(Linking)&rft.au=DAOUD-PINEAU,%20Frederic&COPPRY,%20Maider&MOORE,%20Nicholas&ROGUES,%20Anne-Marie&rft.genre=article


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