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Temporal trends in living kidney donation in France between 2007 and 2017

dc.rights.licenseopenen_US
dc.contributor.authorGAILLARD, F.
dc.contributor.authorJACQUEMONT, L.
dc.contributor.authorROBERTS, V.
dc.contributor.authorALBANO, L.
dc.contributor.authorALLARD, J.
dc.contributor.authorBOUVIER, N.
dc.contributor.authorBUCHLER, M.
dc.contributor.authorTITECA-BEAUPORT, D.
hal.structure.identifierImmunology from Concept and Experiments to Translation [ImmunoConcept]
dc.contributor.authorCOUZI, Lionel
dc.contributor.authorDELAHOUSSE, M.
dc.contributor.authorDUCLOUX, D.
dc.contributor.authorDURRBACH, A.
dc.contributor.authorETIENNE, I.
dc.contributor.authorFRIMAT, L.
dc.contributor.authorGARROUSTE, C.
dc.contributor.authorGRIMBERT, P.
dc.contributor.authorHAZZAN, M.
dc.contributor.authorHERTIG, A.
dc.contributor.authorKAMAR, N.
dc.contributor.authorQUINTREC, M.L.
dc.contributor.authorMARIAT, C.
dc.contributor.authorMOAL, V.
dc.contributor.authorMOULIN, B.
dc.contributor.authorMOUSSON, C.
dc.contributor.authorPOUTEIL-NOBLE, C.
dc.contributor.authorRIEU, P.
dc.contributor.authorROSTAING, L.
dc.contributor.authorTHIERRY, A.
dc.contributor.authorVIGNEAU, C.
dc.contributor.authorMACHER, M.A.
dc.contributor.authorHOURMANT, M.
dc.contributor.authorLEGENDRE, C.
dc.date.accessioned2022-05-09T09:31:07Z
dc.date.available2022-05-09T09:31:07Z
dc.date.issued2021-03
dc.identifier.issn0931-0509en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/140000
dc.description.abstractEnBACKGROUND: Long-term studies have demonstrated a slight increased risk for end-stage renal disease (ESRD) for living kidney donors (LKD). In France, living kidney donation doubled within the past 10 years. We investigated the change in characteristics of LKD between 2007 and 2017 and the adequacy of follow-up. METHODS: Data were obtained from the national registry for LKD. We compared characteristics of LKD between two study periods: 2007-11 and 2012-17, and stratified donors by age and relation to recipient. We aggregated four characteristics associated with higher ESRD risk [young age, first-degree relation to recipient, obesity, low glomerular filtration rate (GFR) for age] in a single risk indicator ranging from 0 to 4. RESULTS: We included 3483 donors. The proportion of unrelated donors >56 years of age increased significantly. The proportion of related donors <56 years of age decreased significantly. The body mass index and proportion of obese donors did not change significantly. The proportion of donors with low estimated GFR for age decreased significantly from 5% to 2.2% (P < 0.001). The proportion of donors with adequate follow-up after donation increased from 19.6% to 42.5% (P < 0.001). No donor had a risk indicator equal to 4, and the proportion of donors with a risk indicator equal to 0 increased significantly from 19.2% to 24.9% (P < 0.001). CONCLUSIONS: An increase in living kidney donation in France does not seem to be associated with the selection of donors at higher risk of ESRD and the proportion of donors with adequate annual follow-up significantly increased.
dc.language.isoENen_US
dc.subject.enFrance
dc.subject.enLiving kidney donors
dc.subject.enTemporal trends
dc.title.enTemporal trends in living kidney donation in France between 2007 and 2017
dc.typeArticle de revueen_US
dc.identifier.doi10.1093/ndt/gfz229en_US
dc.subject.halSciences du Vivant [q-bio]/Immunologieen_US
dc.identifier.pubmed31778191en_US
bordeaux.journalNephrology Dialysis Transplantationen_US
bordeaux.page730-738en_US
bordeaux.volume36en_US
bordeaux.hal.laboratoriesImmunoConcEpT - UMR 5164en_US
bordeaux.issue4en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03662303
hal.version1
hal.date.transferred2022-05-09T09:31:10Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
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