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dc.rights.licenseopenen_US
dc.contributor.authorBARRE, Tangui
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorMERCIE, Patrick
dc.contributor.authorLIONS, Caroline
dc.contributor.authorMIAILHES, Patrick
dc.contributor.authorZUCMAN, David
dc.contributor.authorAUMAITRE, Hugues
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorESTERLE, Laure
dc.contributor.authorSOGNI, Philippe
dc.contributor.authorCARRIERI, Patrizia
dc.contributor.authorSALMON-CERON, Dominique
dc.contributor.authorMARCELLIN, Fabienne
dc.date.accessioned2022-04-25T12:26:01Z
dc.date.available2022-04-25T12:26:01Z
dc.date.issued2022-03-15
dc.identifier.issn1742-6405 (Electronic) 1742-6405 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/139923
dc.description.abstractEnBACKGROUND: Thanks to direct-acting antivirals, hepatitis C virus (HCV) infection can be cured, with similar rates in HCV-infected and HIV-HCV co-infected patients. HCV cure is likely to foster behavioral changes in psychoactive substance use, which is highly prevalent in people living with HIV (PLWH). Cannabis is one substance that is very commonly used by PLWH, sometimes for therapeutic purposes. We aimed to identify correlates of cannabis use reduction following HCV cure in HIV-HCV co-infected cannabis users and to characterize persons who reduced their use. METHODS: We used data collected on HCV-cured cannabis users in a cross-sectional survey nested in the ANRS CO13 HEPAVIH cohort of HIV-HCV co-infected patients, to perform logistic regression, with post-HCV cure cannabis reduction as the outcome, and socio-behavioral characteristics as potential correlates. We also characterized the study sample by comparing post-cure substance use behaviors between those who reduced their cannabis use and those who did not. RESULTS: Among 140 HIV-infected cannabis users, 50 and 5 had reduced and increased their use, respectively, while 85 had not changed their use since HCV cure. Cannabis use reduction was significantly associated with tobacco use reduction, a decrease in fatigue level, paying more attention to one's dietary habits since HCV cure, and pre-HCV cure alcohol abstinence (p = 0.063 for alcohol use reduction). CONCLUSIONS: Among PLWH using cannabis, post-HCV cure cannabis reduction was associated with tobacco use reduction, improved well-being, and adoption of healthy behaviors. The management of addictive behaviors should therefore be encouraged during HCV treatment.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enCannabis
dc.subject.enMarijuana
dc.subject.enHIV
dc.subject.enHepatitis C
dc.subject.enSustained virological response
dc.subject.enHCV cure
dc.subject.enSmoking
dc.subject.enBehavioral changes
dc.title.enHCV cure: an appropriate moment to reduce cannabis use in people living with HIV? (ANRS CO13 HEPAVIH data)
dc.typeArticle de revueen_US
dc.identifier.doi10.1186/s12981-022-00440-9en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed35292069en_US
bordeaux.journalAIDS Research and Therapyen_US
bordeaux.volume19en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue1en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDAgence Nationale de Recherches sur le Sida et les Hépatites Viralesen_US
hal.identifierhal-03651038
hal.version1
hal.date.transferred2022-04-25T12:26:06Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=AIDS%20Research%20and%20Therapy&rft.date=2022-03-15&rft.volume=19&rft.issue=1&rft.eissn=1742-6405%20(Electronic)%201742-6405%20(Linking)&rft.issn=1742-6405%20(Electronic)%201742-6405%20(Linking)&rft.au=BARRE,%20Tangui&MERCIE,%20Patrick&LIONS,%20Caroline&MIAILHES,%20Patrick&ZUCMAN,%20David&rft.genre=article


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