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hal.structure.identifierLaboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC]
dc.contributor.authorJALLOT, Edouard
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorMORETTO, P.
dc.date.issued2006
dc.date.conference2005-10-13
dc.description.abstractEnThe prerequisite for bioactive glasses to bond to living bone is the formation of biologically active apatites on their surface in the body. Reactions and bioactivity mechanisms between bioactive glasses and bone depend on the glass composition. We study a glass in the SiO2-Na2O-CaO-P2O5-K2O-Al2O3-MgO system. To characterise physico-chemical reactions at the materials periphery, we immersed the glass pastilles into biological fluids for delays of 5, 10 and 20 days. The surface changes were studied at the micrometer scale by Particles Induced X-ray Emission (PIXE) method associated to Rutherford Backscattering Spectroscopy (RBS). After 20 days of immersion, elemental maps showed the formation of a calcium-phosphate layer at the surface of the glass pastilles. The thickness of this layer was around 15 µm. Thanks to PIXE method, we demonstrated the presence of traces of Mg in this layer. The glass doped with MgO leads to the formation of an apatite which incorporates magnesium. Formation of this Ca-P-Mg layer represents the bioactive properties of the studied glass. This biologically active layer improves the properties of the glass and will permit a chemical bond between the ceramic and bone.
dc.language.isoen
dc.source.titleInstrumentation Science and Technology
dc.subject.enPIXE
dc.subject.enRBS
dc.subject.enBioactive glass
dc.subject.enBioactivity
dc.subject.enBiomaterials
dc.subject.enDissolution
dc.subject.enApatite
dc.title.enCharacterisation by PIXE method of trace elements during physico-chemical reactions at the periphery of bioactive glass pastilles in contact with biological fluids
dc.typeCommunication dans un congrès
dc.identifier.doi10.1080/10739140600648803
dc.subject.halPhysique [physics]/Physique [physics]/Biophysique [physics.bio-ph]
bordeaux.journalInstrumentation Science & Technology
bordeaux.page405-416
bordeaux.volume34
bordeaux.countryGR
bordeaux.title.proceedingInstrumentation Science and Technology
bordeaux.conference.cityAthens
bordeaux.peerReviewedoui
hal.identifierin2p3-00025081
hal.version1
hal.invitednon
hal.proceedingsoui
hal.conference.end2005-10-15
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//in2p3-00025081v1
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