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hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorINCERTI, S.
hal.structure.identifierInstitut Rayonnement Matière de Saclay (DRF) [IRAMIS]
dc.contributor.authorBALDACCHINO, G.
dc.contributor.authorBERNAL, M.
hal.structure.identifierLaboratoire de physique moléculaire et des collisions [LPMC]
dc.contributor.authorCAPRA, R.
hal.structure.identifierLaboratoire de physique moléculaire et des collisions [LPMC]
dc.contributor.authorCHAMPION, C.
hal.structure.identifierInstitut de Radioprotection et de Sûreté Nucléaire [IRSN]
dc.contributor.authorFRANCIS, Z.
dc.contributor.authorGUEYE, P.
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorMANTERO, A.
dc.contributor.authorMASCIALINO, B.
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorMORETTO, P.
hal.structure.identifierEuropean Space Research and Technology Centre [ESTEC]
dc.contributor.authorNIEMINEN, P.
hal.structure.identifierInstitut de Radioprotection et de Sûreté Nucléaire [IRSN]
dc.contributor.authorVILLAGRASA, C.
dc.contributor.authorZACHARATOU, C.
dc.date.issued2010
dc.identifier.issn1793-9623
dc.description.abstractEnThe Geant4-DNA project proposes to develop an open-source simulation software based and fully included in the general-purpose Geant4 Monte-Carlo simulation toolkit. The main objective of this software is to simulate biological damages induced by ionizing radiations at the cellular and sub-cellular scale. This project was originally initiated by the European Space Agency for the prediction of the deleterious effects of radiations that may affect astronauts during future long duration space exploration missions. In this paper, the Geant4-DNA collaboration presents an overview of the whole on-going project, including its most recent developments that are available in the Geant4 toolkit since December 2009 (release 9.3), as well as an illustration example simulating the direct irradiation of a biological chromatin fiber. Expected extensions involving several research domains, such as particle physics, chemistry and cellular and molecular biology, within a fully interdisciplinary activity of the Geant4 collaboration are also discussed.
dc.language.isoen
dc.publisherWorld Scientific Publishing
dc.title.enThe GEANT4-DNA Project
dc.typeArticle de revue
dc.identifier.doi10.1142/S1793962310000122
dc.subject.halPhysique [physics]/Physique [physics]/Biophysique [physics.bio-ph]
bordeaux.journalInternational Journal of Modeling, Simulation, and Scientific Computing
bordeaux.page157-178
bordeaux.volume1
bordeaux.peerReviewedoui
hal.identifierin2p3-00497683
hal.version1
hal.popularnon
hal.audienceNon spécifiée
dc.subject.esMonte-Carlo
dc.subject.esGeant4
dc.subject.esmicrodosimetry
dc.subject.esnanodosimetry
dc.subject.esradiobiology
hal.origin.linkhttps://hal.archives-ouvertes.fr//in2p3-00497683v1
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