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Modeling Radiation Chemistry and Biology in the Geant4 Toolkit

hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorKARAMITROS, M.
dc.contributor.authorMANTERO, A.
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorINCERTI, S.
hal.structure.identifierInstitut Rayonnement Matière de Saclay (DRF) [IRAMIS]
dc.contributor.authorBALDACCHINO, G.
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorBARBERET, P.
dc.contributor.authorBERNAL, M.
dc.contributor.authorCAPRA, R.
hal.structure.identifierLaboratoire de physique moléculaire et des collisions [LPMC]
dc.contributor.authorCHAMPION, C.
hal.structure.identifierInstitut Pluridisciplinaire Hubert Curien [IPHC]
dc.contributor.authorEL BITAR, Z.
dc.contributor.authorFRANCIS, Z.
dc.contributor.authorFRIEDLAND, W.
dc.contributor.authorGUÈYE, P.
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorIVANCHENKO, A.
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorIVANCHENKO, V.
dc.contributor.authorKURASHIGE, H.
dc.contributor.authorMASCIALINO, B.
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorMORETTO, P.
hal.structure.identifierEuropean Space Research and Technology Centre [ESTEC]
dc.contributor.authorNIEMINEN, P.
hal.structure.identifierEuropean Space Research and Technology Centre [ESTEC]
dc.contributor.authorSANTIN, G.
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorSEZNEC, H.
dc.contributor.authorN. TRAN, H.
hal.structure.identifierInstitut de Radioprotection et de Sûreté Nucléaire [IRSN]
dc.contributor.authorVILLAGRASA, C.
dc.contributor.authorZACHARATOU, C.
dc.date.issued2011
dc.date.conference2010-10-17
dc.description.abstractEnSimulation of biological effects of ionizing radiation at the DNA scale requires not only the modeling of direct damages induced on DNA by the incident radiation and by secondary particles but also the modeling of indirect effects of radiolytic products resulting from water radiolysis. They can provoke single and double strand breaks by reacting with DNA. The Geant4 Monte Carlo toolkit is currently being extended for the simulation of biological damages of ionizing radiation at the DNA scale in the framework of the "Geant4-DNA" project. Physics models for the modeling of direct effects are already available in Geant4. In the present paper, an approach for the modeling of radiation chemistry in pure liquid water within Geant4 is presented. In particular, this modeling includes Brownian motion and chemical reactions between molecules following water radiolysis. First results on time-dependent radiochemical yields1 from 1 picosecond up to 1 microsecond after irradiation are compared to published data and discussed.
dc.language.isoen
dc.source.titleProgress in Nuclear Science and Technology
dc.subject.enGeant4
dc.subject.enGeant4-DNA
dc.subject.enDNA
dc.subject.enmicrodosimetry
dc.subject.enliquid water
dc.subject.enchemistry
dc.subject.enradiolysis
dc.subject.enbiology
dc.subject.enradiation
dc.subject.endamage
dc.title.enModeling Radiation Chemistry and Biology in the Geant4 Toolkit
dc.typeCommunication dans un congrès
dc.subject.halPhysique [physics]/Physique [physics]/Physique Médicale [physics.med-ph]
bordeaux.page503-508
bordeaux.volume2
bordeaux.countryJP
bordeaux.title.proceedingProgress in Nuclear Science and Technology
bordeaux.conference.cityTokyo
bordeaux.peerReviewedoui
hal.identifierin2p3-00658865
hal.version1
hal.invitednon
hal.proceedingsoui
hal.conference.end2010-10-20
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//in2p3-00658865v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.btitle=Progress%20in%20Nuclear%20Science%20and%20Technology&rft.date=2011&rft.volume=2&rft.spage=503-508&rft.epage=503-508&rft.au=KARAMITROS,%20M.&MANTERO,%20A.&INCERTI,%20S.&BALDACCHINO,%20G.&BARBERET,%20P.&rft.genre=unknown


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