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dc.contributor.authorKOSIOR, E.
hal.structure.identifierEuropean Synchrotron Radiation Facility [ESRF]
dc.contributor.authorCLOETENS, P.
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorDEVÈS, Guillaume
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorORTEGA, R.
hal.structure.identifierEuropean Synchrotron Radiation Facility [ESRF]
hal.structure.identifierGrenoble Institut des Neurosciences [GIN]
dc.contributor.authorBOHIC, S.
dc.date.issued2012
dc.identifier.issn0003-6951
dc.description.abstractEnHard X-ray fluorescence microscopy and magnified phase contrast imaging are combined to study radiation effects on cells. Experiments were performed on freeze-dried cells at the nano-imaging station ID22NI of the European synchrotron radiation facility. Quantitative phase contrast imaging provides maps of the projected mass and is used to evaluate the structural changes due to irradiation during X-ray fluorescence experiments. Complementary to phase contrast imaging, scanning transmission ion microscopy is performed and doses of all the experiments are compared. We demonstrate the sensitivity of the proposed approach to study radiation-induced damage at the sub-cellular level.
dc.language.isoen
dc.publisherAmerican Institute of Physics
dc.title.enStudy of radiation effects on the cell structure and evaluation of the dose delivered by x-ray and a-particles microscopy
dc.typeArticle de revue
dc.identifier.doi10.1063/1.4773181
dc.subject.halPhysique [physics]/Physique [physics]/Biophysique [physics.bio-ph]
bordeaux.journalApplied Physics Letters
bordeaux.page263102
bordeaux.volume101
bordeaux.peerReviewedoui
hal.identifierin2p3-00771027
hal.version1
hal.popularnon
hal.audienceNon spécifiée
hal.origin.linkhttps://hal.archives-ouvertes.fr//in2p3-00771027v1
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