Protein-Protein Interactions Focused Libraries for Drug Discovery
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en
Autre document
Este ítem está publicado en
2013-09-16
Resumen en inglés
iPPI TreeTM library was designed using decision tree algorithm based on several molecular shape and functional group descriptors. iPPI AnalogsTM library was prepared by similarity search (ECFP4 fingerprints, minimum Tanimoto ...Leer más >
iPPI TreeTM library was designed using decision tree algorithm based on several molecular shape and functional group descriptors. iPPI AnalogsTM library was prepared by similarity search (ECFP4 fingerprints, minimum Tanimoto index is 0.4) with known active PPI inhibitors from TIMBAL database.< Leer menos
Palabras clave en inglés
Protein-protein interactions
cancer
inflammation
autoimmune diseases
diabetes
osteoporosis
infection
inhibitors
compound libraries
Orígen
Importado de HalCentros de investigación