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Colloidal Apatite Particles : A Multifunctional Platform in (Nano)Medicine

hal.structure.identifierCentre interuniversitaire de recherche et d'ingenierie des matériaux [CIRIMAT]
dc.contributor.authorDROUET, Christophe
hal.structure.identifierCentre interuniversitaire de recherche et d'ingenierie des matériaux [CIRIMAT]
hal.structure.identifierAir liquide France Industrie
dc.contributor.authorCHOIMET, Maëla
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorSIMON, Marina
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorDEVÈS, Guillaume
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorBARBERET, Philippe
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorSEZNEC, Hervé
hal.structure.identifierUniversità degli Studi di Sassari = University of Sassari [Sassari] [UNISS]
dc.contributor.authorRASSU, Giovanna
hal.structure.identifierCentre interuniversitaire de recherche et d'ingenierie des matériaux [CIRIMAT]
dc.contributor.authorMARSAN, Olivier
hal.structure.identifierCentre interuniversitaire de recherche et d'ingenierie des matériaux [CIRIMAT]
dc.contributor.authorTOURRETTE, Audrey
dc.date.issued2020
dc.identifier.issn2575-856X
dc.description.abstractEnCalcium phosphate apatites are naturally present in all vertebrates, as a biomineral in teeth and bones. The possibility to prepare synthetic analogs in close-to-physiological conditions allows the development of bio-inspired materials for medical use. While apatite-based biomaterials are extensively developed for bone regeneration, their intrinsic biocompatibility also allows designing original applications as in nanomedicine. In this paper, we will illustrate why colloidal apatite particles can be seen as a multifunctional platform for (nano)medical uses, well beyond bone repair. Retrospective data will be summarized in this mini-review, especially relating to oncology and hematology applications of apatite colloidal particles. Then novel data will be presented, in the field of dermatology and of particle tracking, using Raman confocal microscopy and μPIXE elemental mapping on substituted apatites. By exploiting their exceptional surface and bulk reactivities, colloidal apatite particles appear as robust new comers to nanomedicine, with the capacity to exhibit tailorable functionalities.
dc.language.isoen
dc.publisherJuniper Publishers
dc.subject.enApatite
dc.subject.enBiomimetism
dc.subject.enNanoparticles
dc.subject.enNanomedicine
dc.subject.enColloid
dc.subject.enOncology
dc.subject.enHematology
dc.subject.enDermatology
dc.subject.enPlatform
dc.subject.enMultifunctional
dc.title.enColloidal Apatite Particles : A Multifunctional Platform in (Nano)Medicine
dc.typeArticle de revue
dc.identifier.doi10.19080/JOJMS.2020.06.555676
dc.subject.halSciences de l'ingénieur [physics]/Matériaux
dc.subject.halSciences du Vivant [q-bio]/Ingénierie biomédicale/Biomatériaux
bordeaux.journalJunipr Online Journal Material Science
bordeaux.page555676
bordeaux.volume6
bordeaux.issue1
bordeaux.peerReviewedoui
hal.identifierhal-03146968
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-03146968v1
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