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Co-Occurrence of Geriatric Syndromes and Diseases in the General Population: Assessment of the Dimensions of Aging

dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDARTIGUES, Jean-Francois
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLE BOURDONNEC, Kateline
dc.contributor.authorTABUE TEGUO, Maturin
ORCID: 0000-0002-1211-5660
IDREF: 175400768
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLE GOFF, Melanie
ORCID: 0000-0003-2848-6287
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorHELMER, Catherine
dc.contributor.authorAVILA-FUNES, Jose Alberto
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorCOUREAU, Gaelle
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorFEART-COURET, Catherine
ORCID: 0000-0002-7959-1610
IDREF: 08195848X
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorPERES, Karine
ORCID: 0000-0002-0720-0684
IDREF: 080634001
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorGENUER, Robin
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLETENNEUR, Luc
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorAMIEVA, Helene
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorPROUST-LIMA, Cecile
dc.date.accessioned2022-02-09T13:21:16Z
dc.date.available2022-02-09T13:21:16Z
dc.date.issued2021-12-31
dc.identifier.issn1279-7707en_US
dc.identifier.urioai:crossref.org:10.1007/s12603-021-1722-3
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/124687
dc.description.abstractEnObjectives : The co-occurrence of multiple medical or psychosocial conditions (geriatric syndromes (GS) and age-related diseases) is a growing concern in older people. Given the diversity of these conditions and their complex interactions, our aim was to determine whether they could be structured into synthetic dimensions in order to facilitate the management of multimorbidity. Design : The underlying structure of 10 GSs and 8 age-related diseases was identified using a multiple correspondence analysis (MCA), and confronted to subjective and objective health outcomes. Setting : Community residents from Bordeaux City (France) older than 75 years in 2010 Participants : 630 adults aged 75+ years who lived in Bordeaux and participated in the 10-year follow-up of the Three-City study. Measurements : GSs included physical frailty, cognitive impairment and dementia, dependency, depressive symptoms, polymedication, thinness, falls, sensory deficit, social isolation, incontinence. Age-related diseases were cancer, cardiac diseases, peripheral vascular diseases, diabetes, hypertension, pulmonary diseases, osteoporosis, other chronic diseases. Association of the MCA-derived independent dimensions was assessed with 10-year visit subjective health and well-being, and with incident death and entry into institution during the remaining cohort follow-up. Results : Most of the participants (82%) had at least two age-related syndromes or diseases. The MCA structured the 18 conditions into three major dimensions: Degradation (D) driven by GS, Vascular (V), and Psychosocial (P) representing 68.7%, 7.4%, and 5.7% of the total variance, respectively. Dimension D was a strong predictor of future death and institutionalization. Dimensions D and P were strongly associated with current well-being. Conclusions : This work confirmed that multimorbidity is very common among older adults, and demonstrated the essential role of GS as manifestations of aging, even more than age-related diseases.
dc.language.isoENen_US
dc.sourcecrossref
dc.subject.enGeriatrics syndrome
dc.subject.enage-related diseases
dc.subject.encohort study
dc.subject.endeath
dc.subject.eninstitution
dc.title.enCo-Occurrence of Geriatric Syndromes and Diseases in the General Population: Assessment of the Dimensions of Aging
dc.title.alternativeJ Nutr Health Agingen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s12603-021-1722-3en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologieen_US
dc.identifier.pubmed35067701en_US
bordeaux.journalJournal of Nutrition, Health and Agingen_US
bordeaux.page37-45en_US
bordeaux.volume26en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue1en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamBIOSTAT_BPHen_US
bordeaux.teamSISTM_BPH
bordeaux.teamACTIVE_BPHen_US
bordeaux.teamEPICENE_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcedissemin
hal.identifierhal-03563092
hal.version1
hal.date.transferred2022-02-09T13:21:19Z
hal.exporttrue
workflow.import.sourcedissemin
dc.rights.ccPas de Licence CCen_US
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