Polyphenolic characterization of merlot, tannat and syrah skin extracts at different degrees of maturity and anti-inflammatory potential in RAW 264.7 cells
| dc.rights.license | open | en_US |
| dc.contributor.author | BENBOUGUERRA, Nawel | |
| hal.structure.identifier | Unité de Recherche Oenologie [Villenave d'Ornon] [OENO] | |
| dc.contributor.author | VALLS FONAYET, Josep | |
| hal.structure.identifier | Unité de Recherche Oenologie [Villenave d'Ornon] [OENO] | |
| dc.contributor.author | KRISA, Stephanie | |
| dc.contributor.author | GARCIA, François | |
| dc.contributor.author | SAUCIER, Cédric | |
| hal.structure.identifier | Unité de Recherche Oenologie [Villenave d'Ornon] [OENO] | |
| dc.contributor.author | RICHARD, Tristan | |
| hal.structure.identifier | Unité de Recherche Oenologie [Villenave d'Ornon] [OENO] | |
| dc.contributor.author | HORNEDO-ORTEGA, Ruth | |
| dc.date.accessioned | 2022-01-05T15:53:44Z | |
| dc.date.available | 2022-01-05T15:53:44Z | |
| dc.date.issued | 2021-03-05 | |
| dc.identifier.issn | 2304-8158 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/124325 | |
| dc.description.abstractEn | (1) Background: Both sensory quality and healthy attributes of Vitis vinifera grapes used for winemaking are closely related with the polyphenolic composition of their skins. (2) Methods: In this study, the polyphenolic characterization (flavan-3-ols, procyanidins, flavonols, stilbenes, anthocyanins) was investigated by ultra performance liquid chromatography coupled to a triple quadrupole mass spectrometer (UPLC-QqQ-MS). Skins from Vitis vinifera Merlot, Tannat, and Syrah red grape varieties cultivated in the south of France at different stages of ripening in 2018 were used. The anti-inflammatory and the antioxidant potential of the extracts were evaluated by the measure of nitric oxide (NO) and the intracellular reactive oxygen species production (ROS) in lipopolysaccharide (LPS)-stimulated macrophages. (3) Results: 41 polyphenols were quantified in all samples. Generally, the flavan-3-ol and procyanidin content decreased during ripening whereas the anthocyanins and stilbenes increased. In addition, as a novelty of this work, a wide identification and characterization of monomeric and oligomeric stilbenes was assessed by using authentic standards isolated in our laboratory, some of them (parthenocissin A and miyabenol C) reported for the first time in Merlot, Tannat and Syrah cultivars. The before-veraison skin extracts of all studied varieties, exhibited higher NO and ROS productions inhibition (>50%) proving both antioxidant and antiinflammatory properties. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.subject.en | Phenolic compounds | |
| dc.subject.en | Vitis vinifera | |
| dc.subject.en | Ripening | |
| dc.subject.en | Grapes | |
| dc.subject.en | Anti-inflammatory | |
| dc.subject.en | Antioxidant activity | |
| dc.title.en | Polyphenolic characterization of merlot, tannat and syrah skin extracts at different degrees of maturity and anti-inflammatory potential in RAW 264.7 cells | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.3390/foods10030541 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Biologie végétale | en_US |
| dc.identifier.pubmed | 33807735 | en_US |
| bordeaux.journal | Foods | en_US |
| bordeaux.volume | 10 | en_US |
| bordeaux.hal.laboratories | Unité de Recherche Oenologie - EA 4577 | en_US |
| bordeaux.issue | 3 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | Bordeaux INP | en_US |
| bordeaux.institution | INRAE | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.export | false | |
| dc.rights.cc | CC BY | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Foods&rft.date=2021-03-05&rft.volume=10&rft.issue=3&rft.eissn=2304-8158&rft.issn=2304-8158&rft.au=BENBOUGUERRA,%20Nawel&VALLS%20FONAYET,%20Josep&KRISA,%20Stephanie&GARCIA,%20Fran%C3%A7ois&SAUCIER,%20C%C3%A9dric&rft.genre=article |
