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Pigments test strips: A rapid companion test to exclude sub-arachnoid haemorrhage

dc.rights.licenseopenen_US
dc.contributor.authorBOUTIN, Julian
hal.structure.identifierBiologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases
dc.contributor.authorBATS, Marie-Lise
dc.contributor.authorAMINTAS, Samuel
dc.contributor.authorBÉRARD, Annie
dc.contributor.authorDABERNAT, Sandrine
dc.contributor.authorCOLOMBIES, Brigitte
dc.contributor.authorRUCHETON, Benoit
dc.contributor.authorBEDEL, Aurélie
dc.date.accessioned2020-10-19T14:03:58Z
dc.date.available2020-10-19T14:03:58Z
dc.date.issued2020
dc.identifier.issn1873-3492en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/11430
dc.description.abstractEnOBJECTIVES: Subarachnoid haemorrhage (SAH) is characterised by 25% of mortality or induces long-term care. It needs immediate diagnosis with computed tomography (CT) scan. For the inconclusive CT scans, the detection of haem pigments can be performed in the cerebrospinal fluid (CSF). The reference method is spectrophotometry but it requires a large volume of CSF, and specific equipment. Sometimes, urine test strips are used as an alternative method for haem pigments detection. However, this method needs validation in SAH context. The aim of the study was to compare the performance of Multistix® urine test strips for haem pigments detection to the reference spectrophotometry and the final clinical SAH diagnosis. METHODS: We collected 136 CSFs sampled for suspected SAH. We detected haem pigments with urine test strips and spectrophotometry and compared performances for 100 samples. RESULTS: Urine tests strips displayed a high sensitivity (0.97) as compared to the reference spectrophotometry for haem pigments detection. Interestingly, absence of haem pigments fully correlated with absence of SAH. CONCLUSIONS: Negative Multistix® urine test strips could help to exclude SAH diagnosis in combination with clinical data when a spectrophotometer is not available, or as a bedside diagnosis test.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial 3.0 United Statesen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/us/en
dc.subjectHaem pigments detection
dc.subjectMultistix® urine test strips
dc.subjectSpectrophotometry
dc.subjectSubarachnoid haemorrhage
dc.subject.enClinique
dc.title.enPigments test strips: A rapid companion test to exclude sub-arachnoid haemorrhage
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.cca.2020.06.052en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologieen_US
dc.identifier.pubmed32622970en_US
bordeaux.journalClinica Chimica Actaen_US
bordeaux.page54–59en_US
bordeaux.hal.laboratoriesBiologie des maladies cardiovasculaires - U1034en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03194411
hal.version1
hal.date.transferred2021-04-09T13:09:34Z
hal.exporttrue
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