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Esophageal Atresia and Respiratory Morbidity

dc.rights.licenseopenen_US
dc.contributor.authorLEJEUNE, Stephanie
dc.contributor.authorSFEIR, Rony
dc.contributor.authorROUSSEAU, Veronique
dc.contributor.authorBONNARD, Arnaud
dc.contributor.authorGELAS, Thomas
dc.contributor.authorAUMAR, Madeleine
dc.contributor.authorPANAIT, Nicoleta
dc.contributor.authorRABATTU, Pierre-Yves
dc.contributor.authorIRTAN, Sabine
dc.contributor.authorFOUQUET, Virginie
dc.contributor.authorLE MANDAT, Aurelie
dc.contributor.authorCOCCI, Stephane De Napoli
dc.contributor.authorHABONIMANA, Edouard
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLAMIREAU, Thierry
dc.contributor.authorLEMELLE, Jean-Louis
dc.contributor.authorELBAZ, Frederic
dc.contributor.authorTALON, Isabelle
dc.contributor.authorBOUDAOUD, Nadia
dc.contributor.authorALLAL, Hossein
dc.contributor.authorBUISSON, Philippe
dc.contributor.authorPETIT, Thierry
dc.contributor.authorSAPIN, Emmanuel
dc.contributor.authorLARDY, Hubert
dc.contributor.authorSCHMITT, Francoise
dc.contributor.authorLEVARD, Guillaume
dc.contributor.authorSCALABRE, Aurelien
dc.contributor.authorMICHEL, Jean-Luc
dc.contributor.authorJABY, Olivier
dc.contributor.authorPELATAN, Cecile
dc.contributor.authorDE VRIES, Philine
dc.contributor.authorBORDERON, Corinne
dc.contributor.authorFOURCADE, Laurent
dc.contributor.authorBREAUD, Jean
dc.contributor.authorARNOULD, Myriam
dc.contributor.authorTOLG, Cecilia
dc.contributor.authorCHAUSSY, Yann
dc.contributor.authorGEISS, Stephan
dc.contributor.authorLAPLACE, Christophe
dc.contributor.authorDRUMEZ, Elodie
dc.contributor.authorEL MOURAD, Sawsan
dc.contributor.authorTHUMERELLE, Caroline
dc.contributor.authorGOTTRAND, Frederic
dc.date.accessioned2021-10-11T08:59:31Z
dc.date.available2021-10-11T08:59:31Z
dc.date.issued2021-08-19
dc.identifier.issn0031-4005en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/112714
dc.description.abstractEnBACKGROUND AND OBJECTIVES: Respiratory diseases are common in children with esophageal atresia (EA), leading to increased morbidity and mortality in the first year. The primary study objective was to identify the factors associated with readmissions for respiratory causes in the first year in EA children. METHODS: A population-based study. We included all children born between 2008 and 2016 with available data and analyzed factors at birth and 1 year follow-up. Factors with a P value <.10 in univariate analyses were retained in logistic regression models. RESULTS: Among 1460 patients born with EA, 97 (7%) were deceased before the age of 1 year, and follow-up data were available for 1287 patients, who constituted our study population. EAs were Ladd classification type III or IV in 89%, preterm birth was observed in 38%, and associated malformations were observed in 52%. Collectively, 61% were readmitted after initial discharge in the first year, 31% for a respiratory cause. Among these, respiratory infections occurred in 64%, and 35% received a respiratory treatment. In logistic regression models, factors associated with readmission for a respiratory cause were recurrence of tracheoesophageal fistula, aortopexy, antireflux surgery, and tube feeding; factors associated with respiratory treatment were male sex and laryngeal cleft. CONCLUSIONS: Respiratory morbidity in the first year after EA repair is frequent, accounting for >50% of readmissions. Identifying high risk groups of EA patients (ie, those with chronic aspiration, anomalies of the respiratory tract, and need for tube feeding) may guide follow-up strategies.
dc.language.isoENen_US
dc.title.enEsophageal Atresia and Respiratory Morbidity
dc.typeArticle de revueen_US
dc.identifier.doi10.1542/peds.2020-049778en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed34413249en_US
bordeaux.journalPediatricsen_US
bordeaux.volume148en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue3en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamLEHA_BPH
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03372882
hal.version1
hal.date.transferred2021-10-11T08:59:44Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.jtitle=Pediatrics&amp;rft.date=2021-08-19&amp;rft.volume=148&amp;rft.issue=3&amp;rft.eissn=0031-4005&amp;rft.issn=0031-4005&amp;rft.au=LEJEUNE,%20Stephanie&amp;SFEIR,%20Rony&amp;ROUSSEAU,%20Veronique&amp;BONNARD,%20Arnaud&amp;GELAS,%20Thomas&amp;rft.genre=article


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