TANTOT, Frederic; PARKES, Shauna; MARCHAND, Alain; BOITARD, Chloe; NANEIX, Fabien; LAYE, Sophie; TRIFILIEFF, Pierre; COUTUREAU, Etienne; FERREIRA, Guillaume

doi:10.1016/j.appet.2016.10.001

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TANTOT, Frederic
Nutrition et Neurobiologie intégrée [NutriNeuro]

PARKES, Shauna

Institut de Neurosciences cognitives et intégratives d'Aquitaine [INCIA]

MARCHAND, Alain

Institut de Neurosciences cognitives et intégratives d'Aquitaine [INCIA]

Langue

Article de revue

Ce document a été publié dans

Appetite. 2017, vol. 108, p. 203-211

Résumé en anglais

Evidence now indicates that the chronic consumption of high-calorie foods, such as a high-fat diet (HFD), is associated with impaired control over food-seeking, yet the extent of this alteration is not fully understood. Using different reinforcement schedules, we evaluated whether HFD intake from weaning to adulthood modifies instrumental responding and induces a shift from goal-directed actions to habitual responding. We first observed reduced instrumental performance and motivation for a food reward in HFD-fed rats trained under schedules of reinforcement that facilitate habitual responding [Random Interval (RI)]. However, this deficit was alleviated if rats trained under RI were subsequently trained with reinforcement schedules that promote goal-directed strategies [Random Ratio (RR)]. Using an outcome devaluation procedure, we then demonstrated that consumption of a HFD promoted habitual behavior in rats trained under RI but not RR schedules. Finally, extended HFD exposure did not interfere with the ability of RR training to overcome impaired RI instrumental performance and to favor goal-directed behavior. These results indicate that chronic consumption of a HFD changes the co-ordination of goal-directed actions and habits and that alteration of food-seeking may be reversed under particular behavioral conditions.< Réduire

Mots clés en anglais

Action

Animals

Appetitive Behavior

Cognition Disorders

Diet

High-Fat

Feeding Behavior

Habit

Learning Disabilities

Male

Obesity

Operant conditioning

Outcome devaluation

Rats

Long-Evans

Reinforcement Schedule

Reward

Time Factors

Weaning

Conditioning Operant

URI

https://oskar-bordeaux.fr/handle/20.500.12278/112142

DOI

http://dx.doi.org/10.1016/j.appet.2016.10.001

Projet Européen

International Mobility Programme to Strengthen Skills and Excellence in Research for Agriculture

Project ANR

Bases neuronales du comportement dirigé vers un but chez le Rat
Impact neuro-cognitif de l'obésité juvénile: approches expérimentale et clinique

Unités de recherche

NutriNeuro (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286