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dc.rights.licenseopenen_US
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorJOFFRE, Corinne
dc.contributor.authorGREGOIRE, Stephane
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorDE SMEDT-PEYRUSSE, Veronique
dc.contributor.authorACAR, Niyazi
dc.contributor.authorBRETILLON, Lionel
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorNADJAR, Agnes
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorLAYE, Sophie
ORCID: 0000-0002-3843-1012
IDREF: 11366883X
dc.date.accessioned2021-09-08T06:56:00Z
dc.date.available2021-09-08T06:56:00Z
dc.date.issued2016-11
dc.identifier.issn1532-2823en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/112138
dc.description.abstractEnThe relative amounts of arachidonic acid (AA) and docosahexaenoic acid (DHA) govern the different functions of the brain. Their brain levels depend on structures considered, on fatty acid dietary supply and the age of animals. To have a better overview of the different models available in the literature we here compared the brain fatty acid composition in various mice models (C57BL/6J, CD1, Fat-1, SAMP8 mice) fed with different n-3 PUFA diets (deficient, balanced, enriched) in adults and aged animals. Our results demonstrated that brain AA and DHA content is 1) structure-dependent; 2) strain-specific; 3) differently affected by dietary approaches when compared to genetic model of PUFA modulation; 4) different in n-3 PUFA deficient aged C57BL6/J when compared to SAMP8 mouse model of aging. From these experiments, we highlight the difficulty to compare results obtained in different mouse models, different strains, different brain regions and different ages.
dc.language.isoENen_US
dc.subject.enAging
dc.subject.enAnimals
dc.subject.enArachidonic Acid
dc.subject.enArachidonic acid (AA)
dc.subject.enBrain Chemistry
dc.subject.enBrain regions
dc.subject.enBrain Stem
dc.subject.enCerebellum
dc.subject.enCerebral Cortex
dc.subject.enDocosahexaenoic acid (DHA)
dc.subject.enDocosahexaenoic Acids
dc.subject.enFat-1 mice
dc.subject.enFemale
dc.subject.enHippocampus
dc.subject.enHypothalamus
dc.subject.enMale
dc.subject.enMice
dc.subject.enN-3 PUFA
dc.subject.enPrefrontal Cortex
dc.subject.enSAMP8 mice
dc.subject.enDietary Fats Unsaturated
dc.subject.enMice Inbred C57BL
dc.subject.enModels Theoretical
dc.title.enModulation of brain PUFA content in different experimental models of mice
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.plefa.2016.09.003en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed27926457en_US
bordeaux.journalProstaglandins, Leukotrienes and Essential Fatty Acidsen_US
bordeaux.page1-10en_US
bordeaux.volume114en_US
bordeaux.hal.laboratoriesNutriNeurO (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINRAEen_US
bordeaux.teamPsychoneuroimmunologie et Nutrition: Approches expérimentales et cliniquesen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Prostaglandins,%20Leukotrienes%20and%20Essential%20Fatty%20Acids&rft.date=2016-11&rft.volume=114&rft.spage=1-10&rft.epage=1-10&rft.eissn=1532-2823&rft.issn=1532-2823&rft.au=JOFFRE,%20Corinne&GREGOIRE,%20Stephane&DE%20SMEDT-PEYRUSSE,%20Veronique&ACAR,%20Niyazi&BRETILLON,%20Lionel&rft.genre=article


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