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dc.relation.isnodoublee161f7ae-3a22-4c22-b30d-4967d71f1dd8*
dc.contributor.authorHABENSTEIN, Birgit
dc.contributor.authorLOQUET, Antoine
dc.date.accessioned2020-09-03T07:56:17Z
dc.date.available2020-09-03T07:56:17Z
dc.date.issued2016
dc.identifier.issn0301-4622
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/10866
dc.description.abstractEnProtein self-assemblies are ubiquitous biological systems involved in many cellular processes, ranging from bacterial and viral infection to the propagation of neurodegenerative disorders. Studying the atomic three-dimensional structures of protein self-assemblies is a particularly demanding task, as these systems are usually insoluble, non-crystalline and of large size. Solid-state NMR (ssNMR) is an emerging method that can provide atomic-level structural data on intact macromolecular assemblies. We here present recent progress in magic angle spinning ssNMR to study protein assemblies and give an overview on its combination with complementary techniques such as cryo-EM, mass-per-length measurements, SAXS and X-ray diffraction. Applications of ssNMR on its own and in hybrid approaches have revealed precious atomic details and first high-resolution structures of complex biological assemblies, including amyloid fibrils, bacterial filaments, phages or virus capsids. (C) 2015 Elsevier B.V. All rights reserved.
dc.language.isoen
dc.title.enSolid-state NMR: An emerging technique in structural biology of self-assemblies
dc.typeArticle de revue
dc.identifier.doi10.1016/j.bpc.2015.07.003
dc.subject.halChimie/Matériaux
bordeaux.journalBiophysical Chemistry
bordeaux.page14-26
bordeaux.volume210
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248*
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN, UMR 5248)
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Biophysical%20Chemistry&rft.date=2016&rft.volume=210&rft.spage=14-26&rft.epage=14-26&rft.eissn=0301-4622&rft.issn=0301-4622&rft.au=HABENSTEIN,%20Birgit&LOQUET,%20Antoine&rft.genre=article


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