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dc.contributor.authorLE SAUX, Guillaume
dc.contributor.authorPLAWINSKI, Laurent
dc.contributor.authorNLATE, Sylvain
dc.contributor.authorRIPOCHE, Jean
dc.contributor.authorBUFFETEAU, Thierry
dc.contributor.authorDURRIEU, Marie-Christine
dc.date.accessioned2020-09-03T07:56:13Z
dc.date.available2020-09-03T07:56:13Z
dc.date.issued2016
dc.identifier.issn1932-6203
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/10849
dc.description.abstractEnIntravascular devices for continuous glucose monitoring are promising tools for the follow up and treatment of diabetic patients. Limiting the inflammatory response to the implanted devices in order to achieve better biocompatibility is a critical challenge. Herein we report on the production and the characterization of gold surfaces covalently derivatized with the peptide alpha-alpha-melanocyte stimulating hormone (alpha-MSH), with a quantifiable surface density. In vitro study demonstrated that the tethered alpha-MSH is able to decrease the expression of an inflammatory cytokine produced by endothelial cells.
dc.language.isoen
dc.title.enBeneficial Effect of Covalently Grafted alpha-MSH on Endothelial Release of Inflammatory Mediators for Applications in Implantable Devices
dc.typeArticle de revue
dc.identifier.doi10.1371/journal.pone.0150706
dc.subject.halChimie/Matériaux
bordeaux.journalPlos One
bordeaux.volume11
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248*
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN, UMR 5248)
bordeaux.issue3
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Plos%20One&rft.date=2016&rft.volume=11&rft.issue=3&rft.eissn=1932-6203&rft.issn=1932-6203&rft.au=LE%20SAUX,%20Guillaume&PLAWINSKI,%20Laurent&NLATE,%20Sylvain&RIPOCHE,%20Jean&BUFFETEAU,%20Thierry&rft.genre=article


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