Mostrar el registro sencillo del ítem

dc.rights.licenseopenen_US
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorCABANNE, Charlotte
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorSANTARELLI, Xavier
dc.date.accessioned2021-07-12T15:25:53Z
dc.date.available2021-07-12T15:25:53Z
dc.date.issued2019
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/106529
dc.description.abstractEnMixed mode chromatography resins with salt tolerance, large design space and orthogonal selectivity requires a slightly more complex development than traditional resins. It is important to screen several ligands and several binding and elution conditions. This allows taking full advantage of these resins. High-Throughput Screening (HTS) for Process Development should be done with the help of Design of Experiment (DoE). It could be performed in filter plates or Robocolumns, and assisted by liquid handling automated workstation. Modeling of the results allows the choice of optimal parameters that can then be validated and scaled up. All this leads to a better knowledge and robustness of the purification step.
dc.language.isoENen_US
dc.subject.enMixed mode chromatography
dc.subject.enhigh throughput process development
dc.subject.endesign of experiment
dc.subject.enlarge opportunities
dc.subject.enHigh-Throughput Screening (HTS)
dc.subject.enDesign of Experiment (DoE)
dc.title.enMixed Mode Chromatography, Complex Development for Large Opportunities
dc.typeArticle de revueen_US
dc.identifier.doi10.2174/1389203718666171030104211en_US
dc.subject.halChimie/Matériauxen_US
bordeaux.journalCurrent protein & peptide scienceen_US
bordeaux.page22-27en_US
bordeaux.volume20en_US
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248en_US
bordeaux.issue1en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionCNRS
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-02503996
hal.exportfalse
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Current%20protein%20&%20peptide%20science&rft.date=2019&rft.volume=20&rft.issue=1&rft.spage=22-27&rft.epage=22-27&rft.au=CABANNE,%20Charlotte&SANTARELLI,%20Xavier&rft.genre=article


Archivos en el ítem

ArchivosTamañoFormatoVer

No hay archivos asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem